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    RpL4 Ribosomal protein L4 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43349, updated on 17-Dec-2024

    Summary

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    Official Symbol
    RpL4provided by FlyBase
    Official Full Name
    Ribosomal protein L4provided by FlyBase
    Primary source
    FLYBASE:FBgn0003279
    Locus tag
    Dmel_CG5502
    See related
    AllianceGenome:FB:FBgn0003279
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-WO0172774.76; CG5502; chr3R:23749174..23749334; Dmel\CG5502; L4; Rp L4; rpL1; RpL1
    Summary
    A structural constituent of ribosome. Predicted to be involved in cytoplasmic translation. Located in cytosolic ribosome. Is expressed in adult head; adult heart; organism; and spermatozoon. Orthologous to human RPL4 (ribosomal protein L4). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See RpL4 in Genome Data Viewer
    Location:
    98B6-98B6; 3-94 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (27922821..27924888)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (23748543..23750610)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene BCAS2 Neighboring gene ncRNA Neighboring gene long non-coding RNA:CR45566 Neighboring gene minotaur Neighboring gene nenya Neighboring gene antisense RNA:CR46452

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Sequence of the ribosomal protein cDNA of D. melanogaster homologous to the L1 ribosomal protein gene of X. laevis. Rafti F, et al. Nucleic Acids Res, 1989 Jan 11. PMID 2492096, Free PMC Article
    2. Isolation and structural analysis of a ribosomal protein gene in D.melanogaster. Rafti F, et al. Nucleic Acids Res, 1988 Jun 10. PMID 3133637, Free PMC Article
    3. Isolation and mapping of a cloned ribosomal protein gene of Drosophila melanogaster. Vaslet CA, et al. Nature, 1980 Jun 26. PMID 6771656
    4. The Zinc-BED Transcription Factor Bedwarfed Promotes Proportional Dendritic Growth and Branching through Transcriptional and Translational Regulation in Drosophila. Bhattacharjee S, et al. Int J Mol Sci, 2023 Mar 28. PMID 37047316, Free PMC Article
    5. Attenuated Codon Optimality Contributes to Neural-Specific mRNA Decay in Drosophila. Burow DA, et al. Cell Rep, 2018 Aug 14. PMID 30110627, Free PMC Article

    See all (82) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome HDA PubMed 
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables structural constituent of ribosome TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cytoplasmic translation IC
    Inferred by Curator
    more info
    		 PubMed 
    involved_in cytoplasmic translation TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of cytosolic large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of cytosolic large ribosomal subunit TAS
    Traceable Author Statement
    more info
    		 PubMed 
    located_in cytosolic ribosome HDA PubMed 
    located_in cytosolic ribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ribosomal protein L4
    Names
    60S RIBOSOMAL PROTEIN L4
    CG5502-PA
    RpL4-PA
    ribosomal protein L1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      27922821..27924888
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_079814.3 → NP_524538.2  ribosomal protein L4 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_524538.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P09180, Q9I7H6
      Related
      FBpp0084617
      Conserved Domains (1) summary
      PTZ00428
      Location:6 → 383
      PTZ00428; 60S ribosomal protein L4; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P09180.2 P09180

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