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    Actr6 actin related protein 6 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 314718, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Actr6provided by RGD
    Official Full Name
    actin related protein 6provided by RGD
    Primary source
    RGD:1304609
    See related
    EnsemblRapid:ENSRNOG00000007875 AllianceGenome:RGD:1304609
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable nucleosome binding activity. Predicted to be involved in nucleolus organization. Predicted to be located in nucleolus. Predicted to be part of Swr1 complex. Orthologous to human ACTR6 (actin related protein 6). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Adrenal (RPKM 211.9), Brain (RPKM 105.5) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Actr6 in Genome Data Viewer
    Location:
    7q13
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (26037574..26058362, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (24150250..24171057, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (30377369..30397922, complement)

    Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134479656 Neighboring gene uncharacterized LOC134479655 Neighboring gene bridge-like lipid transfer protein family member 3B Neighboring gene ankyrin repeat and sterile alpha motif domain containing 1B Neighboring gene U2 spliceosomal RNA

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. The INO80 family of chromatin-remodeling enzymes: regulators of histone variant dynamics. Watanabe S, et al. Cold Spring Harb Symp Quant Biol, 2010. PMID 21502417
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables nucleosome binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in nucleolus organization ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    part_of Swr1 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    actin-related protein 6
    Names
    ARP6 actin-related protein 6 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001108081.1 → NP_001101551.1  actin-related protein 6

      See identical proteins and their annotated locations for NP_001101551.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473960
      UniProtKB/TrEMBL
      B2RYQ1, F7F615
      Related
      ENSRNOP00000092687.2, ENSRNOT00000118790.2
      Conserved Domains (1) summary
      smart00268
      Location:2 → 394
      ACTIN; Actin

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086025.1 Reference GRCr8

      Range
      26037574..26058362 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006241243.3 → XP_006241305.2  actin-related protein 6 isoform X1

      UniProtKB/TrEMBL
      A0A8I6AE58

    2. XM_039079042.2 → XP_038934970.1  actin-related protein 6 isoform X2

      Conserved Domains (1) summary
      smart00268
      Location:10 → 312
      ACTIN; Actin

    3. XM_039079041.1 → XP_038934969.1  actin-related protein 6 isoform X2

      Conserved Domains (1) summary
      smart00268
      Location:10 → 312
      ACTIN; Actin
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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