FSTL1 follistatin like 1 [Gallus gallus (chicken)] - Gene

Summary

Symbol: FSTL1provided by CGNC
Full Name: follistatin like 1provided by CGNC
Primary source: CGNC:11120
See related: Ensembl:ENSGALG00010025032
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as: FLIK
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 1

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	1	NC_052532.1 (79921802..79965421)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	1	NC_052573.1 (80107334..80150996)

Chromosome 1 - NC_052532.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Suggest role for Follistatin-like1 in controlling late heart muscle cell formation in chick embryo.
Title: Patterns of expression of the Follistatin and Follistatin-like1 genes during chicken heart development: a potential role in valvulogenesis and late heart muscle cell formation.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables protein binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in cell differentiation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in multicellular organism development	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of BMP signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in extracellular space	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: follistatin-related protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_204638.3 → NP_989969.3 follistatin-related protein 1 precursor

Status: VALIDATED

Source sequence(s)

JAENSK010000017

UniProtKB/TrEMBL

A0A8V1A1C6

Related

ENSGALP00010037819.1, ENSGALT00010061129.1

Conserved Domains (4) summary

smart00274
Location:31 → 53

FOLN; Follistatin-N-terminal domain-like

smart00280
Location:54 → 98

KAZAL; Kazal type serine protease inhibitors

cd16233
Location:113 → 226

EFh_SPARC_FSTL1; EF-hand, extracellular calcium-binding (EC) motif, found in follistatin-related protein 1 (FRP-1)

cl17735
Location:233 → 271

VWC; von Willebrand factor type C domain