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    CYP2C23a cytochrome P450, family 2, subfamily C, polypeptide 23a [ Gallus gallus (chicken) ]

    Gene ID: 414746, updated on 24-Feb-2024

    Summary

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    Gene symbol
    CYP2C23a
    Gene description
    cytochrome P450, family 2, subfamily C, polypeptide 23a
    See related
    Ensembl:ENSGALG00010020676
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    CYP2C8; CYP2H1; CYPIIH1
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    Genomic context

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    See CYP2C23a in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 6 NC_052537.1 (18351042..18358414, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 6 NC_052578.1 (18337055..18344427, complement)

    Chromosome 6 - NC_052537.1Genomic Context describing neighboring genes Neighboring gene biogenesis of lysosomal organelles complex 1 subunit 2 Neighboring gene cytochrome P450 family 2 subfamily C member 23b Neighboring gene uncharacterized LOC124418053 Neighboring gene uncharacterized LOC107053667 Neighboring gene uncharacterized LOC121111218 Neighboring gene uncharacterized LOC101749984

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The cDNA and protein sequence of a phenobarbital-induced chicken cytochrome P-450. Hobbs AA, et al. J Biol Chem, 1986 Jul 15. PMID 2424910
    2. Partial cloning of CYP2C23a genes and hepatic protein expression in eight representative avian species. Watanabe KP, et al. J Vet Pharmacol Ther, 2015 Apr. PMID 25229839
    3. Conservation of signaling pathways of xenobiotic-sensing orphan nuclear receptors, chicken xenobiotic receptor, constitutive androstane receptor, and pregnane X receptor, from birds to humans. Handschin C, et al. Mol Endocrinol, 2001 Sep. PMID 11518807
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    5. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in organic acid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in xenobiotic metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in intracellular membrane-bounded organelle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cytochrome P450 2H1
    Names
    cytochrome P450 2C23a
    cytochrome P450 2C8
    cytochrome P450 CYP2H1, phenobarbital-inducible
    cytochrome P450 PB15
    cytochrome P450 PCHP3
    cytochrome P450, family 2, subfamily H, polypeptide 1
    putative cytochrome P450 CYP2A6
    NP_001001616.2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001001616.2 → NP_001001616.2  cytochrome P450 2H1

      Status: PROVISIONAL

      Source sequence(s)
      JAENSK010000231
      UniProtKB/Swiss-Prot
      P05180
      UniProtKB/TrEMBL
      A0A8V0ZFD0
      Related
      ENSGALP00010029527.1, ENSGALT00010049987.1
      Conserved Domains (1) summary
      cl12078
      Location:1 → 469
      p450; Cytochrome P450

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052537.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      18351042..18358414 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052578.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      18337055..18344427 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P05180.1 GenPept UniProtKB/Swiss-Prot:P05180

    Gene LinkOut

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    Research Materials