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    SLC30A7 solute carrier family 30 member 7 [ Gallus gallus (chicken) ]

    Gene ID: 424464, updated on 17-Aug-2024

    Summary

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    Symbol
    SLC30A7provided by CGNC
    Full Name
    solute carrier family 30 member 7provided by CGNC
    Primary source
    CGNC:14346
    See related
    Ensembl:ENSGALG00010023652
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    ZNT7
    Orthologs
    human mouse all
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    Genomic context

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    See SLC30A7 in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 8 NC_052539.1 (11471654..11498604, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 8 NC_052580.1 (11479514..11506464, complement)

    Chromosome 8 - NC_052539.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119771270 Neighboring gene sphingosine-1-phosphate receptor 1 Neighboring gene microRNA 1610 Neighboring gene diphthamide biosynthesis 5 Neighboring gene uncharacterized LOC124418140 Neighboring gene exostosin like glycosyltransferase 2 Neighboring gene cell division cycle 14A

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Zinc transport complexes contribute to the homeostatic maintenance of secretory pathway function in vertebrate cells. Ishihara K, et al. J Biol Chem, 2006 Jun 30. PMID 16636052
    2. Zinc transporters, ZnT5 and ZnT7, are required for the activation of alkaline phosphatases, zinc-requiring enzymes that are glycosylphosphatidylinositol-anchored to the cytoplasmic membrane. Suzuki T, et al. J Biol Chem, 2005 Jan 7. PMID 15525635
    3. Two different zinc transport complexes of cation diffusion facilitator proteins localized in the secretory pathway operate to activate alkaline phosphatases in vertebrate cells. Suzuki T, et al. J Biol Chem, 2005 Sep 2. PMID 15994300
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    5. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. contributes to the conversion of apo-alkaline phosphatase to holo-alkaline phosphatase
      Title: Zinc transporters, ZnT5 and ZnT7, are required for the activation of alkaline phosphatases, zinc-requiring enzymes that are glycosylphosphatidylinositol-anchored to the cytoplasmic membrane.
    2. ZnT5(-)ZnT7(-/-) cells showed exacerbation of the unfolded protein response as did the wild-type cells cultured under a zinc-deficient condition, revealing that both complexes play a role in homeostatic maintenance of secretory pathway function
      Title: Zinc transport complexes contribute to the homeostatic maintenance of secretory pathway function in vertebrate cells.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables zinc ion transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular zinc ion homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in zinc ion transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    zinc transporter 7
    Names
    solute carrier family 30 (zinc transporter), member 7
    znT-7

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001008788.2 → NP_001008788.1  zinc transporter 7

      See identical proteins and their annotated locations for NP_001008788.1

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000239
      UniProtKB/Swiss-Prot
      Q5MNV6
      Conserved Domains (2) summary
      COG1230
      Location:31 → 374
      CzcD; Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism]
      pfam01545
      Location:48 → 296
      Cation_efflux; Cation efflux family

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052539.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      11471654..11498604 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046944424.1 → XP_046800380.1  zinc transporter 7 isoform X3

    2. XM_046944423.1 → XP_046800379.1  zinc transporter 7 isoform X1

      UniProtKB/Swiss-Prot
      Q5MNV6
      Related
      ENSGALP00010034989.1, ENSGALT00010057609.1

    3. XM_015290612.4 → XP_015146098.2  zinc transporter 7 isoform X2

      Conserved Domains (1) summary
      COG1230
      Location:1 → 304
      CzcD; Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism]

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052580.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      11479514..11506464 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046922615.1 → XP_046778571.1  zinc transporter 7 isoform X3

    2. XM_046922613.1 → XP_046778569.1  zinc transporter 7 isoform X1

      UniProtKB/Swiss-Prot
      Q5MNV6

    3. XM_046922614.1 → XP_046778570.1  zinc transporter 7 isoform X2

    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5MNV6.1 GenPept UniProtKB/Swiss-Prot:Q5MNV6

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.