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    GPM6B glycoprotein M6B [ Gallus gallus (chicken) ]

    Gene ID: 418632, updated on 3-Dec-2024

    Summary

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    Symbol
    GPM6Bprovided by CGNC
    Full Name
    glycoprotein M6Bprovided by CGNC
    Primary source
    CGNC:50810
    See related
    Ensembl:ENSGALG00010002393
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    M6b
    Orthologs
    human mouse all
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    Genomic context

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    See GPM6B in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 1 NC_052532.1 (122952084..123058423)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 1 NC_052573.1 (122934358..123021630)

    Chromosome 1 - NC_052532.1Genomic Context describing neighboring genes Neighboring gene maestro heat-like repeat-containing protein family member 2B like 3 Neighboring gene gem nuclear organelle associated protein 8 Neighboring gene OFD1, centriole and centriolar satellite protein Neighboring gene trafficking protein particle complex 2 Neighboring gene RAB9A, member RAS oncogene family

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Evolution of myelin proteolipid proteins: gene duplication in teleosts and expression pattern divergence. Schweitzer J, et al. Mol Cell Neurosci, 2006 Jan. PMID 16289898
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables structural constituent of myelin sheath IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in axon development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in central nervous system myelination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in myelin sheath IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    neuronal membrane glycoprotein M6-b
    Names
    DMgamma
    proteolipid GPM6B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001012545.2 → NP_001012563.1  neuronal membrane glycoprotein M6-b isoform h

      See identical proteins and their annotated locations for NP_001012563.1

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000023
      UniProtKB/TrEMBL
      A0A8V0XFC6, Q5EES2
      Conserved Domains (1) summary
      pfam01275
      Location:3 → 239
      Myelin_PLP; Myelin proteolipid protein (PLP or lipophilin)

    2. NM_001397181.1 → NP_001384110.1  neuronal membrane glycoprotein M6-b isoform a

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000023
      UniProtKB/TrEMBL
      A0A8V0XFC6
      Conserved Domains (1) summary
      pfam01275
      Location:62 → 298
      Myelin_PLP; Myelin proteolipid protein (PLP or lipophilin)

    3. NM_001397182.1 → NP_001384111.1  neuronal membrane glycoprotein M6-b isoform b

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000023
      UniProtKB/TrEMBL
      A0A8V0XFC6
      Related
      ENSGALP00010003340.1, ENSGALT00010005501.1
      Conserved Domains (1) summary
      pfam01275
      Location:43 → 279
      Myelin_PLP; Myelin proteolipid protein (PLP or lipophilin)

    4. NM_001397183.1 → NP_001384112.1  neuronal membrane glycoprotein M6-b isoform c

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000023
      UniProtKB/TrEMBL
      A0A1D5P175, A0A8V0X9M0
      Related
      ENSGALP00010003333.1, ENSGALT00010005494.1
      Conserved Domains (1) summary
      pfam01275
      Location:62 → 298
      Myelin_PLP; Myelin proteolipid protein (PLP or lipophilin)

    5. NM_001397184.1 → NP_001384113.1  neuronal membrane glycoprotein M6-b isoform d

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000023
      UniProtKB/TrEMBL
      A0A8V0X9M0, F6V444
      Related
      ENSGALP00010003339.1, ENSGALT00010005500.1
      Conserved Domains (1) summary
      smart00002
      Location:184 → 244
      PLP; Myelin proteolipid protein (PLP or lipophilin)

    6. NM_001397185.1 → NP_001384114.1  neuronal membrane glycoprotein M6-b isoform e

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000023
      UniProtKB/TrEMBL
      A0A8V0X5K5, A0A8V0X9M0
      Related
      ENSGALP00010003332.1, ENSGALT00010005493.1
      Conserved Domains (1) summary
      smart00002
      Location:183 → 243
      PLP; Myelin proteolipid protein (PLP or lipophilin)

    7. NM_001397186.1 → NP_001384115.1  neuronal membrane glycoprotein M6-b isoform f

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000023
      UniProtKB/TrEMBL
      A0A8V0X5K9, A0A8V0XFC6
      Related
      ENSGALP00010003337.1, ENSGALT00010005498.1
      Conserved Domains (1) summary
      smart00002
      Location:151 → 211
      PLP; Myelin proteolipid protein (PLP or lipophilin)

    8. NM_001397188.1 → NP_001384117.1  neuronal membrane glycoprotein M6-b isoform g

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000023
      UniProtKB/TrEMBL
      A0A8V0XFC6
      Conserved Domains (1) summary
      pfam01275
      Location:22 → 258
      Myelin_PLP; Myelin proteolipid protein (PLP or lipophilin)

    9. NM_001397189.1 → NP_001384118.1  neuronal membrane glycoprotein M6-b isoform i

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000023
      UniProtKB/TrEMBL
      A0A8V0X9M0, A0A8V0XCM2
      Related
      ENSGALP00010003334.1, ENSGALT00010005495.1
      Conserved Domains (1) summary
      smart00002
      Location:163 → 223
      PLP; Myelin proteolipid protein (PLP or lipophilin)

    10. NM_001397190.1 → NP_001384119.1  neuronal membrane glycoprotein M6-b isoform j

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000023
      UniProtKB/TrEMBL
      A0A8V0X9M0
      Related
      ENSGALP00010003336.1, ENSGALT00010005497.1
      Conserved Domains (1) summary
      smart00002
      Location:144 → 204
      PLP; Myelin proteolipid protein (PLP or lipophilin)

    11. NM_001397191.1 → NP_001384120.1  neuronal membrane glycoprotein M6-b isoform k

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000023
      Conserved Domains (1) summary
      smart00002
      Location:77 → 137
      PLP; Myelin proteolipid protein (PLP or lipophilin)

    12. NM_001397192.1 → NP_001384121.1  neuronal membrane glycoprotein M6-b isoform l

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000023
      Conserved Domains (1) summary
      smart00002
      Location:77 → 137
      PLP; Myelin proteolipid protein (PLP or lipophilin)

    13. NM_001397193.1 → NP_001384122.1  neuronal membrane glycoprotein M6-b isoform l

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000023
      Conserved Domains (1) summary
      smart00002
      Location:77 → 137
      PLP; Myelin proteolipid protein (PLP or lipophilin)

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      122952084..123058423
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046940759.1 → XP_046796715.1  neuronal membrane glycoprotein M6-b isoform X8

      UniProtKB/TrEMBL
      A0A8V0XG63

    2. XM_046940764.1 → XP_046796720.1  neuronal membrane glycoprotein M6-b isoform X10

      UniProtKB/TrEMBL
      A0A8V0X9M0
      Related
      ENSGALP00010003338.1, ENSGALT00010005499.1

    3. XM_046940765.1 → XP_046796721.1  neuronal membrane glycoprotein M6-b isoform X11

      UniProtKB/TrEMBL
      A0A8V0X9M0

    4. XM_046940762.1 → XP_046796718.1  neuronal membrane glycoprotein M6-b isoform X9

      UniProtKB/TrEMBL
      A0A8V0XFC6

    5. XM_046940755.1 → XP_046796711.1  neuronal membrane glycoprotein M6-b isoform X5

      UniProtKB/TrEMBL
      A0A8V0XFC6

    6. XM_046940748.1 → XP_046796704.1  neuronal membrane glycoprotein M6-b isoform X2

      UniProtKB/TrEMBL
      A0A8V0XFC6

    7. XM_046940747.1 → XP_046796703.1  neuronal membrane glycoprotein M6-b isoform X1

      UniProtKB/TrEMBL
      A0A8V0XFC6

    8. XM_046940757.1 → XP_046796713.1  neuronal membrane glycoprotein M6-b isoform X7

      UniProtKB/TrEMBL
      A0A8V0X9M0

    9. XM_046940753.1 → XP_046796709.1  neuronal membrane glycoprotein M6-b isoform X4

      UniProtKB/TrEMBL
      A0A8V0XFC6

    10. XM_046940756.1 → XP_046796712.1  neuronal membrane glycoprotein M6-b isoform X6

      UniProtKB/TrEMBL
      A0A8V0XFC6
      Conserved Domains (1) summary
      pfam01275
      Location:37 → 272
      Myelin_PLP; Myelin proteolipid protein (PLP or lipophilin)

    11. XM_046940751.1 → XP_046796707.1  neuronal membrane glycoprotein M6-b isoform X3

      UniProtKB/TrEMBL
      A0A8V0XFC6

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      122934358..123021630
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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