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    GLS2 glutaminase 2 [ Gallus gallus (chicken) ]

    Gene ID: 424043, updated on 3-Dec-2024

    Summary

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    Symbol
    GLS2provided by CGNC
    Full Name
    glutaminase 2provided by CGNC
    Primary source
    CGNC:5698
    See related
    Ensembl:ENSGALG00010013872
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    GLS
    Orthologs
    human mouse all
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    Genomic context

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    See GLS2 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 7 NC_052538.1 (7458284..7513693)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 7 NC_052579.1 (7382208..7437642)

    Chromosome 7 - NC_052538.1Genomic Context describing neighboring genes Neighboring gene nascent polypeptide-associated complex subunit alpha, muscle-specific form-like Neighboring gene adenosine deaminase, RNA specific B1 Neighboring gene uncharacterized LOC101747789 Neighboring gene signal transducer and activator of transcription 1 Neighboring gene signal transducer and activator of transcription 4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A comprehensive collection of chicken cDNAs. Boardman PE, et al. Curr Biol, 2002 Nov 19. PMID 12445392
    2. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables glutaminase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in glutamate biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in glutamine catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    glutaminase kidney isoform, mitochondrial
    Names
    glutaminase
    glutaminase C
    NP_001382927.1
    XP_015144876.1
    XP_015144877.1
    XP_046777241.1
    XP_046777242.1
    XP_046777243.1
    XP_046799518.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001395998.1 → NP_001382927.1  glutaminase kidney isoform, mitochondrial precursor

      Status: VALIDATED

      Source sequence(s)
      AJ720678, BU142407, BU294490
      UniProtKB/TrEMBL
      A0A8V0YFM7, Q5ZIV6
      Related
      ENSGALP00010019648.1, ENSGALT00010033282.1
      Conserved Domains (3) summary
      PLN03192
      Location:533 → 619
      PLN03192; Voltage-dependent potassium channel; Provisional
      sd00045
      Location:534 → 560
      ANK; ANK repeat [structural motif]
      cl00907
      Location:208 → 518
      Glutaminase

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052538.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      7458284..7513693
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015289390.4 → XP_015144876.1  glutaminase kidney isoform, mitochondrial isoform X1

      UniProtKB/TrEMBL
      A0A8V0YM08, Q5ZIV6
      Related
      ENSGALP00010019645.1, ENSGALT00010033277.1
      Conserved Domains (4) summary
      cd00204
      Location:560 → 645
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam04960
      Location:247 → 533
      Glutaminase; Glutaminase
      pfam13637
      Location:590 → 642
      Ank_4; Ankyrin repeats (many copies)
      sd00045
      Location:560 → 586
      ANK; ANK repeat [structural motif]

    2. XM_015289391.4 → XP_015144877.1  glutaminase kidney isoform, mitochondrial isoform X2

      Conserved Domains (1) summary
      pfam04960
      Location:247 → 533
      Glutaminase; Glutaminase

    3. XM_046943562.1 → XP_046799518.1  glutaminase kidney isoform, mitochondrial isoform X3

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052579.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      7382208..7437642
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046921285.1 → XP_046777241.1  glutaminase kidney isoform, mitochondrial isoform X1

      UniProtKB/TrEMBL
      A0A8V0YM08, Q5ZIV6

    2. XM_046921286.1 → XP_046777242.1  glutaminase kidney isoform, mitochondrial isoform X2

    3. XM_046921287.1 → XP_046777243.1  glutaminase kidney isoform, mitochondrial isoform X3

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001031248.1: Suppressed sequence

      Description
      NM_001031248.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
    Nucleotide Protein Strain
    Heading Accession and Version

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