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    CDK6 cyclin dependent kinase 6 [ Gallus gallus (chicken) ]

    Gene ID: 420558, updated on 17-Aug-2024

    Summary

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    Symbol
    CDK6provided by CGNC
    Full Name
    cyclin dependent kinase 6provided by CGNC
    Primary source
    CGNC:51286
    See related
    Ensembl:ENSGALG00010005004
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See CDK6 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 2 NC_052533.1 (22606846..22740743, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 2 NC_052574.1 (22637730..22771595, complement)

    Chromosome 2 - NC_052533.1Genomic Context describing neighboring genes Neighboring gene EF-hand calcium binding domain 1 Neighboring gene family with sequence similarity 133 member B Neighboring gene microRNA 1650 Neighboring gene uncharacterized LOC107052572 Neighboring gene uncharacterized LOC112531971 Neighboring gene sterile alpha motif domain containing 9 like Neighboring gene HEPACAM family member 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Retinoic acid promotes proliferation of chicken primordial germ cells via activation of PI3K/Akt-mediated NF-κB signalling cascade. Yu M, et al. Cell Biol Int, 2012 Aug 1. PMID 22548360
    2. Ginsenosides promote proliferation of granulosa cells from chicken prehierarchical follicles through PKC activation and up-regulated cyclin gene expression. Tan TQ, et al. Cell Biol Int, 2010 Jul. PMID 20402666
    3. TDP-43 regulates retinoblastoma protein phosphorylation through the repression of cyclin-dependent kinase 6 expression. Ayala YM, et al. Proc Natl Acad Sci U S A, 2008 Mar 11. PMID 18305152, Free PMC Article
    4. An expressed sequence tag database of T-cell-enriched activated chicken splenocytes: sequence analysis of 5251 clones. Tirunagaru VG, et al. Genomics, 2000 Jun 1. PMID 10860659
    5. A comprehensive collection of chicken cDNAs. Boardman PE, et al. Curr Biol, 2002 Nov 19. PMID 12445392

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables cyclin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables cyclin-dependent protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in G1/S transition of mitotic cell cycle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell dedifferentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of G2/M transition of mitotic cell cycle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of cell population proliferation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of gene expression IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of cyclin-dependent protein kinase holoenzyme complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cyclin-dependent kinase 6
    Names
    cell division protein kinase 6
    NP_001007893.1
    NP_001384302.1
    NP_001384303.1
    NP_001384304.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001007892.4 → NP_001007893.1  cyclin-dependent kinase 6 isoform 1

      See identical proteins and their annotated locations for NP_001007893.1

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000036
      UniProtKB/TrEMBL
      Q90771
      Conserved Domains (1) summary
      cd07862
      Location:11 → 300
      STKc_CDK6; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 6

    2. NM_001397373.1 → NP_001384302.1  cyclin-dependent kinase 6 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000036
      UniProtKB/TrEMBL
      Q90771
      Related
      ENSGALP00010006583.1, ENSGALT00010011760.1
      Conserved Domains (1) summary
      cd07862
      Location:11 → 300
      STKc_CDK6; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 6

    3. NM_001397374.1 → NP_001384303.1  cyclin-dependent kinase 6 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000036
      UniProtKB/TrEMBL
      Q90771
      Conserved Domains (1) summary
      cd07862
      Location:11 → 300
      STKc_CDK6; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 6

    4. NM_001397375.1 → NP_001384304.1  cyclin-dependent kinase 6 isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000036
      UniProtKB/TrEMBL
      A0A8V0XIR1
      Related
      ENSGALP00010006581.1, ENSGALT00010011757.1
      Conserved Domains (1) summary
      cl21453
      Location:11 → 283
      PKc_like; Protein Kinases, catalytic domain

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052533.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      22606846..22740743 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052574.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      22637730..22771595 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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