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    CHRNB3 cholinergic receptor nicotinic beta 3 subunit [ Gallus gallus (chicken) ]

    Gene ID: 395604, updated on 3-Dec-2024

    Summary

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    Symbol
    CHRNB3provided by CGNC
    Full Name
    cholinergic receptor nicotinic beta 3 subunitprovided by CGNC
    Primary source
    CGNC:49397
    See related
    Ensembl:ENSGALG00010012425
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    NACHR
    Orthologs
    human mouse all
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    Genomic context

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    See CHRNB3 in Genome Data Viewer
    Location:
    chromosome: Z
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) Z NC_052572.1 (54303459..54321240, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) Z NC_059536.1 (54303459..54321240, complement)

    Chromosome Z - NC_052572.1Genomic Context describing neighboring genes Neighboring gene iduronidase, alpha-L- Neighboring gene solute carrier family 26 member 1 Neighboring gene cholinergic receptor nicotinic alpha 6 subunit Neighboring gene THAP domain containing 1 Neighboring gene transcription factor AP-1-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Characterization of the nicotinic acetylcholine receptor beta 3 gene. Its regulation within the avian nervous system is effected by a promoter 143 base pairs in length. Hernandez MC, et al. J Biol Chem, 1995 Feb 17. PMID 7852408
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables acetylcholine-gated monoatomic cation-selective channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transmembrane signaling receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chemical synaptic transmission IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in monoatomic ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in nervous system process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of membrane potential IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in neuron projection IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in postsynaptic membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in synapse IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    neuronal acetylcholine receptor subunit beta-3
    Names
    cholinergic receptor, nicotinic, beta 3 (neuronal)
    cholinergic receptor, nicotinic, beta polypeptide 3
    nicotinic acetylcholine receptor (nAChR) beta 3 subunit
    nicotinic acetylcholine receptor beta 3 subunit

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_204812.3 → NP_990143.3  neuronal acetylcholine receptor subunit beta-3 precursor

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000095
      UniProtKB/Swiss-Prot
      P43679
      UniProtKB/TrEMBL
      A0A8V0YML4
      Related
      ENSGALP00010017355.1, ENSGALT00010029809.1
      Conserved Domains (2) summary
      TIGR00860
      Location:1 → 446
      LIC; Cation transporter family protein
      cd19026
      Location:51 → 229
      LGIC_ECD_nAChR_B3; extracellular domain of nicotinic acetylcholine receptor subunit beta 3 (CHRNB3)

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052572.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      54303459..54321240 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040655384.2 → XP_040511318.1  neuronal acetylcholine receptor subunit beta-3 isoform X4

      UniProtKB/Swiss-Prot
      P43679
      UniProtKB/TrEMBL
      A0A8V0YML4
      Conserved Domains (2) summary
      TIGR00860
      Location:1 → 446
      LIC; Cation transporter family protein
      cd19026
      Location:51 → 229
      LGIC_ECD_nAChR_B3; extracellular domain of nicotinic acetylcholine receptor subunit beta 3 (CHRNB3)

    2. XM_025144653.2 → XP_025000421.2  neuronal acetylcholine receptor subunit beta-3 isoform X3

      UniProtKB/TrEMBL
      A0A8V0YHT6
      Conserved Domains (2) summary
      TIGR00860
      Location:43 → 473
      LIC; Cation transporter family protein
      cd19026
      Location:78 → 256
      LGIC_ECD_nAChR_B3; extracellular domain of nicotinic acetylcholine receptor subunit beta 3 (CHRNB3)

    3. XM_040655383.2 → XP_040511317.1  neuronal acetylcholine receptor subunit beta-3 isoform X2

      UniProtKB/TrEMBL
      A0A8V0Y9F1
      Conserved Domains (2) summary
      TIGR00860
      Location:1 → 362
      LIC; Cation transporter family protein
      cd19026
      Location:51 → 229
      LGIC_ECD_nAChR_B3; extracellular domain of nicotinic acetylcholine receptor subunit beta 3 (CHRNB3)

    4. XM_025144652.2 → XP_025000420.2  neuronal acetylcholine receptor subunit beta-3 isoform X1

      Conserved Domains (2) summary
      cd19026
      Location:78 → 256
      LGIC_ECD_nAChR_B3; extracellular domain of nicotinic acetylcholine receptor subunit beta 3 (CHRNB3)
      cd19064
      Location:258 → 347
      LGIC_TM_nAChR; transmembrane domain of nicotinic acetylcholine receptor (nAChR)

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_059536.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      54303459..54321240 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046934746.1 → XP_046790702.1  neuronal acetylcholine receptor subunit beta-3 isoform X4

      UniProtKB/Swiss-Prot
      P43679
      UniProtKB/TrEMBL
      A0A8V0YML4

    2. XM_046934745.1 → XP_046790701.1  neuronal acetylcholine receptor subunit beta-3 isoform X3

      UniProtKB/TrEMBL
      A0A8V0YHT6

    3. XM_046934744.1 → XP_046790700.1  neuronal acetylcholine receptor subunit beta-3 isoform X2

      UniProtKB/TrEMBL
      A0A8V0Y9F1

    4. XM_046934743.1 → XP_046790699.1  neuronal acetylcholine receptor subunit beta-3 isoform X1

    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P43679.2 GenPept UniProtKB/Swiss-Prot:P43679

    Gene LinkOut

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    Molecular Biology Databases
    Research Materials