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    TYRP1 tyrosinase related protein 1 [ Gallus gallus (chicken) ]

    Gene ID: 395913, updated on 17-Aug-2024

    Summary

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    Symbol
    TYRP1provided by CGNC
    Full Name
    tyrosinase related protein 1provided by CGNC
    Primary source
    CGNC:11314
    See related
    Ensembl:ENSGALG00010014092
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    TRP1; TRP-1
    Orthologs
    human mouse all
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    Genomic context

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    See TYRP1 in Genome Data Viewer
    Location:
    chromosome: Z
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) Z NC_052572.1 (31227860..31238589)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) Z NC_059536.1 (31227860..31238589)

    Chromosome Z - NC_052572.1Genomic Context describing neighboring genes Neighboring gene ankyrin repeat domain-containing protein 13C-like Neighboring gene uncharacterized LOC124417545 Neighboring gene leucine rich adaptor protein 1-like Neighboring gene multiple PDZ domain protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A missense mutation in TYRP1 causes the chocolate plumage color in chicken and alters melanosome structure. Li J, et al. Pigment Cell Melanoma Res, 2019 May. PMID 30457703
    2. The cloning and sequencing of a cDNA coding for chick tyrosinase-related protein-1. April CS, et al. Biochim Biophys Acta, 1998 Jan 7. PMID 9434144
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. first TYRP1 mutation described in the chicken
      Title: A missense mutation in TYRP1 causes the chocolate plumage color in chicken and alters melanosome structure.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in melanocyte differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in melanosome organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in melanosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    5,6-dihydroxyindole-2-carboxylic acid oxidase
    Names
    DHICA oxidase
    NP_990376.2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_205045.3 → NP_990376.2  5,6-dihydroxyindole-2-carboxylic acid oxidase precursor

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000092
      UniProtKB/Swiss-Prot
      O57405
      UniProtKB/TrEMBL
      F1NXQ4
      Related
      ENSGALP00010019896.1, ENSGALT00010033822.1
      Conserved Domains (1) summary
      pfam00264
      Location:182 → 416
      Tyrosinase; Common central domain of tyrosinase

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052572.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      31227860..31238589
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_059536.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      31227860..31238589
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O57405.1 GenPept UniProtKB/Swiss-Prot:O57405

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.