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    MCEE methylmalonyl-CoA epimerase [ Gallus gallus (chicken) ]

    Gene ID: 415385, updated on 17-Aug-2024

    Summary

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    Symbol
    MCEEprovided by CGNC
    Full Name
    methylmalonyl-CoA epimeraseprovided by CGNC
    Primary source
    CGNC:2867
    See related
    Ensembl:ENSGALG00010024785
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See MCEE in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 10 NC_052541.1 (5814941..5824763)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 10 NC_052582.1 (5689335..5699157)

    Chromosome 10 - NC_052541.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121111663 Neighboring gene myotubularin related protein 10 Neighboring gene M-phase phosphoprotein 10 Neighboring gene FANCD2/FANCI-associated nuclease 1 Neighboring gene amyloid beta precursor protein binding family A member 2 Neighboring gene family with sequence similarity 189 member A1 Neighboring gene uncharacterized LOC121111664 Neighboring gene tight junction protein 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A comprehensive collection of chicken cDNAs. Boardman PE, et al. Curr Biol, 2002 Nov 19. PMID 12445392
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables methylmalonyl-CoA epimerase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in L-methylmalonyl-CoA metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    methylmalonyl-CoA epimerase, mitochondrial
    NP_001280146.1
    NP_001280147.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001293217.1 → NP_001280146.1  methylmalonyl-CoA epimerase, mitochondrial isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      BX266728, JAENSK010000245
      UniProtKB/TrEMBL
      A0A8V0ZZV0, E1BSK7
      Related
      ENSGALP00010037266.1, ENSGALT00010060507.1
      Conserved Domains (1) summary
      TIGR03081
      Location:57 → 185
      metmalonyl_epim; methylmalonyl-CoA epimerase

    2. NM_001293218.1 → NP_001280147.1  methylmalonyl-CoA epimerase, mitochondrial isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 5' coding region compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
      Source sequence(s)
      BU433401, BX930043, JAENSK010000245
      UniProtKB/TrEMBL
      A0A8V0ZZV0
      Conserved Domains (1) summary
      TIGR03081
      Location:44 → 172
      metmalonyl_epim; methylmalonyl-CoA epimerase

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052541.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      5814941..5824763
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052582.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      5689335..5699157
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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