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    PRPS2 phosphoribosyl pyrophosphate synthetase 2 [ Gallus gallus (chicken) ]

    Gene ID: 418639, updated on 3-Dec-2024

    Summary

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    Symbol
    PRPS2provided by CGNC
    Full Name
    phosphoribosyl pyrophosphate synthetase 2provided by CGNC
    Primary source
    CGNC:50814
    See related
    Ensembl:ENSGALG00010001901
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See PRPS2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 1 NC_052532.1 (123572596..123598464, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 1 NC_052573.1 (123534088..123559955, complement)

    Chromosome 1 - NC_052532.1Genomic Context describing neighboring genes Neighboring gene thymosin beta 4X Neighboring gene toll like receptor 7 Neighboring gene maestro heat-like repeat-containing protein family member 1 Neighboring gene maestro heat-like repeat-containing protein family member 2A

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables magnesium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ribose phosphate diphosphokinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in 5-phosphoribose 1-diphosphate biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in purine nucleotide biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in ribonucleoside monophosphate biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of ribose phosphate diphosphokinase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ribose-phosphate pyrophosphokinase 2
    Names
    PRS-II
    phosphoribosyl pyrophosphate synthase II
    phosphoribosyl pyrophosphate synthetase II
    NP_001006264.1
    XP_015129149.1
    XP_046763968.1
    XP_046763969.1
    XP_046763970.1
    XP_046796750.1
    XP_046796751.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001006264.2 → NP_001006264.1  ribose-phosphate pyrophosphokinase 2

      See identical proteins and their annotated locations for NP_001006264.1

      Status: PROVISIONAL

      Source sequence(s)
      JAENSK010000024
      UniProtKB/Swiss-Prot
      Q5ZI49
      UniProtKB/TrEMBL
      A0A8V0YXK9
      Related
      ENSGALP00010002624.1, ENSGALT00010004346.1
      Conserved Domains (1) summary
      COG0462
      Location:1 → 320
      PrsA; Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism, Amino acid transport and metabolism]

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      123572596..123598464 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015273663.4 → XP_015129149.1  ribose-phosphate pyrophosphokinase 2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0YXK9
      Conserved Domains (1) summary
      COG0462
      Location:1 → 313
      PrsA; Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism, Amino acid transport and metabolism]

    2. XM_046940794.1 → XP_046796750.1  ribose-phosphate pyrophosphokinase 2 isoform X2

    3. XM_046940795.1 → XP_046796751.1  ribose-phosphate pyrophosphokinase 2 isoform X3

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      123534088..123559955 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046908012.1 → XP_046763968.1  ribose-phosphate pyrophosphokinase 2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0YXK9

    2. XM_046908013.1 → XP_046763969.1  ribose-phosphate pyrophosphokinase 2 isoform X2

    3. XM_046908014.1 → XP_046763970.1  ribose-phosphate pyrophosphokinase 2 isoform X3

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5ZI49.1 GenPept UniProtKB/Swiss-Prot:Q5ZI49

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials