U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    FRMPD4 FERM and PDZ domain containing 4 [ Gallus gallus (chicken) ]

    Gene ID: 418640, updated on 17-Aug-2024

    Summary

    Go to the top of the page Help
    Symbol
    FRMPD4provided by CGNC
    Full Name
    FERM and PDZ domain containing 4provided by CGNC
    Primary source
    CGNC:12433
    See related
    Ensembl:ENSGALG00010001925
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See FRMPD4 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 1 NC_052532.1 (123691775..123996020, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 1 NC_052573.1 (123636387..123940553, complement)

    Chromosome 1 - NC_052532.1Genomic Context describing neighboring genes Neighboring gene maestro heat-like repeat-containing protein family member 1 Neighboring gene maestro heat-like repeat-containing protein family member 2B Neighboring gene uncharacterized LOC112531499 Neighboring gene uncharacterized LOC121109499 Neighboring gene uncharacterized LOC124417601 Neighboring gene MSL complex subunit 3

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    FERM and PDZ domain-containing protein 4

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      123691775..123996020 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_416838.8 → XP_416838.4  FERM and PDZ domain-containing protein 4 isoform X1

      UniProtKB/TrEMBL
      A0A8V0X7S1
      Related
      ENSGALP00010002682.1, ENSGALT00010004411.1
      Conserved Domains (6) summary
      smart00295
      Location:205 → 424
      B41; Band 4.1 homologues
      cd00201
      Location:36 → 66
      WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
      cd00992
      Location:76 → 152
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd13183
      Location:420 → 524
      FERM_C_FRMPD1_FRMPD3_FRMPD4; FERM domain C-lobe of FERM and PDZ domain containing proteins 1, 3, and 4 (FRMPD1, 3, 4)
      pfam00373
      Location:300 → 424
      FERM_M; FERM central domain
      pfam16511
      Location:205 → 238
      FERM_f0; N-terminal or F0 domain of Talin-head FERM

    2. XM_040662265.2 → XP_040518199.1  FERM and PDZ domain-containing protein 4 isoform X2

      Conserved Domains (4) summary
      smart00295
      Location:151 → 370
      B41; Band 4.1 homologues
      cd00992
      Location:22 → 98
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd13183
      Location:366 → 470
      FERM_C_FRMPD1_FRMPD3_FRMPD4; FERM domain C-lobe of FERM and PDZ domain containing proteins 1, 3, and 4 (FRMPD1, 3, 4)
      cd17170
      Location:147 → 240
      FERM_F1_FRMPD4; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM and PDZ domain-containing protein 4 (FRMPD4)

    3. XM_040662269.2 → XP_040518203.1  FERM and PDZ domain-containing protein 4 isoform X3

      Conserved Domains (3) summary
      smart00295
      Location:4 → 223
      B41; Band 4.1 homologues
      cd13183
      Location:219 → 323
      FERM_C_FRMPD1_FRMPD3_FRMPD4; FERM domain C-lobe of FERM and PDZ domain containing proteins 1, 3, and 4 (FRMPD1, 3, 4)
      cl28922
      Location:1 → 93
      Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      123636387..123940553 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040662245.2 → XP_040518179.1  FERM and PDZ domain-containing protein 4 isoform X1

      Conserved Domains (5) summary
      smart00295
      Location:205 → 424
      B41; Band 4.1 homologues
      cd00201
      Location:36 → 66
      WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
      cd00992
      Location:76 → 152
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd13183
      Location:420 → 524
      FERM_C_FRMPD1_FRMPD3_FRMPD4; FERM domain C-lobe of FERM and PDZ domain containing proteins 1, 3, and 4 (FRMPD1, 3, 4)
      cd17170
      Location:201 → 294
      FERM_F1_FRMPD4; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM and PDZ domain-containing protein 4 (FRMPD4)

    2. XM_040662247.2 → XP_040518181.1  FERM and PDZ domain-containing protein 4 isoform X2

      Conserved Domains (4) summary
      smart00295
      Location:151 → 370
      B41; Band 4.1 homologues
      cd00992
      Location:22 → 98
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd13183
      Location:366 → 470
      FERM_C_FRMPD1_FRMPD3_FRMPD4; FERM domain C-lobe of FERM and PDZ domain containing proteins 1, 3, and 4 (FRMPD1, 3, 4)
      cd17170
      Location:147 → 240
      FERM_F1_FRMPD4; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM and PDZ domain-containing protein 4 (FRMPD4)

    3. XM_040662248.2 → XP_040518182.1  FERM and PDZ domain-containing protein 4 isoform X3

      Conserved Domains (3) summary
      smart00295
      Location:4 → 223
      B41; Band 4.1 homologues
      cd13183
      Location:219 → 323
      FERM_C_FRMPD1_FRMPD3_FRMPD4; FERM domain C-lobe of FERM and PDZ domain containing proteins 1, 3, and 4 (FRMPD1, 3, 4)
      cl28922
      Location:1 → 93
      Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials