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    L3MBTL3 L3MBTL histone methyl-lysine binding protein 3 [ Gallus gallus (chicken) ]

    Gene ID: 421705, updated on 3-Dec-2024

    Summary

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    Official Symbol
    L3MBTL3provided by CGNC
    Official Full Name
    L3MBTL histone methyl-lysine binding protein 3provided by CGNC
    Primary source
    CGNC:51530
    See related
    Ensembl:ENSGALG00010005275
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See L3MBTL3 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    29
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 3 NC_052534.1 (57552584..57630634, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 3 NC_052575.1 (57462124..57540341, complement)

    Chromosome 3 - NC_052534.1Genomic Context describing neighboring genes Neighboring gene transmembrane protein 200A Neighboring gene sterile alpha motif domain containing 3 Neighboring gene transmembrane protein 244 Neighboring gene uncharacterized LOC121110266 Neighboring gene Rho GTPase activating protein 18

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    lethal(3)malignant brain tumor-like protein 3
    Names
    L3MBTL3, histone methyl-lysine binding protein
    l(3)mbt-like 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052534.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      57552584..57630634 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046939776.1 → XP_046795732.1  lethal(3)malignant brain tumor-like protein 3 isoform X3

      UniProtKB/TrEMBL
      A0A8V0XML3

    2. XM_015284137.4 → XP_015139623.1  lethal(3)malignant brain tumor-like protein 3 isoform X2

      UniProtKB/TrEMBL
      A0A1D5PTN3, A0A8V0XG13
      Related
      ENSGALP00010007074.1, ENSGALT00010012510.1
      Conserved Domains (3) summary
      cd09582
      Location:738 → 803
      SAM_Scm-like-3MBT3,4; SAM domain of Scm-like-3MBT3,4 proteins of Polycomb group
      smart00561
      Location:213 → 309
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      pfam01530
      Location:535 → 563
      zf-C2HC; Zinc finger, C2HC type

    3. XM_040697946.2 → XP_040553880.1  lethal(3)malignant brain tumor-like protein 3 isoform X2

      UniProtKB/TrEMBL
      A0A1D5PTN3, A0A8V0XG13
      Conserved Domains (3) summary
      cd09582
      Location:738 → 803
      SAM_Scm-like-3MBT3,4; SAM domain of Scm-like-3MBT3,4 proteins of Polycomb group
      smart00561
      Location:213 → 309
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      pfam01530
      Location:535 → 563
      zf-C2HC; Zinc finger, C2HC type

    4. XM_040697944.2 → XP_040553878.1  lethal(3)malignant brain tumor-like protein 3 isoform X2

      UniProtKB/TrEMBL
      A0A1D5PTN3, A0A8V0XG13
      Conserved Domains (3) summary
      cd09582
      Location:738 → 803
      SAM_Scm-like-3MBT3,4; SAM domain of Scm-like-3MBT3,4 proteins of Polycomb group
      smart00561
      Location:213 → 309
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      pfam01530
      Location:535 → 563
      zf-C2HC; Zinc finger, C2HC type

    5. XM_040697943.2 → XP_040553877.1  lethal(3)malignant brain tumor-like protein 3 isoform X2

      UniProtKB/TrEMBL
      A0A1D5PTN3, A0A8V0XG13
      Related
      ENSGALP00010007064.1, ENSGALT00010012500.1
      Conserved Domains (3) summary
      cd09582
      Location:738 → 803
      SAM_Scm-like-3MBT3,4; SAM domain of Scm-like-3MBT3,4 proteins of Polycomb group
      smart00561
      Location:213 → 309
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      pfam01530
      Location:535 → 563
      zf-C2HC; Zinc finger, C2HC type

    6. XM_046939775.1 → XP_046795731.1  lethal(3)malignant brain tumor-like protein 3 isoform X2

      UniProtKB/TrEMBL
      A0A1D5PTN3, A0A8V0XG13

    7. XM_015284138.4 → XP_015139624.1  lethal(3)malignant brain tumor-like protein 3 isoform X2

      UniProtKB/TrEMBL
      A0A1D5PTN3, A0A8V0XG13
      Conserved Domains (3) summary
      cd09582
      Location:738 → 803
      SAM_Scm-like-3MBT3,4; SAM domain of Scm-like-3MBT3,4 proteins of Polycomb group
      smart00561
      Location:213 → 309
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      pfam01530
      Location:535 → 563
      zf-C2HC; Zinc finger, C2HC type

    8. XM_040697940.2 → XP_040553874.1  lethal(3)malignant brain tumor-like protein 3 isoform X2

      UniProtKB/TrEMBL
      A0A1D5PTN3, A0A8V0XG13
      Related
      ENSGALP00010007071.1, ENSGALT00010012507.1
      Conserved Domains (3) summary
      cd09582
      Location:738 → 803
      SAM_Scm-like-3MBT3,4; SAM domain of Scm-like-3MBT3,4 proteins of Polycomb group
      smart00561
      Location:213 → 309
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      pfam01530
      Location:535 → 563
      zf-C2HC; Zinc finger, C2HC type

    9. XM_040697941.2 → XP_040553875.1  lethal(3)malignant brain tumor-like protein 3 isoform X2

      UniProtKB/TrEMBL
      A0A1D5PTN3, A0A8V0XG13
      Conserved Domains (3) summary
      cd09582
      Location:738 → 803
      SAM_Scm-like-3MBT3,4; SAM domain of Scm-like-3MBT3,4 proteins of Polycomb group
      smart00561
      Location:213 → 309
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      pfam01530
      Location:535 → 563
      zf-C2HC; Zinc finger, C2HC type

    10. XM_040697942.2 → XP_040553876.1  lethal(3)malignant brain tumor-like protein 3 isoform X2

      UniProtKB/TrEMBL
      A0A1D5PTN3, A0A8V0XG13
      Conserved Domains (3) summary
      cd09582
      Location:738 → 803
      SAM_Scm-like-3MBT3,4; SAM domain of Scm-like-3MBT3,4 proteins of Polycomb group
      smart00561
      Location:213 → 309
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      pfam01530
      Location:535 → 563
      zf-C2HC; Zinc finger, C2HC type

    11. XM_419742.7 → XP_419742.6  lethal(3)malignant brain tumor-like protein 3 isoform X1

      UniProtKB/TrEMBL
      A0A8V0XG13, A0A8V0XK48
      Related
      ENSGALP00010007068.1, ENSGALT00010012504.1
      Conserved Domains (2) summary
      cd09582
      Location:786 → 851
      SAM_Scm-like-3MBT3,4; SAM domain of Scm-like-3MBT3,4 proteins of Polycomb group
      smart00561
      Location:261 → 357
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2

    12. XM_046939774.1 → XP_046795730.1  lethal(3)malignant brain tumor-like protein 3 isoform X2

      UniProtKB/TrEMBL
      A0A1D5PTN3, A0A8V0XG13

    13. XM_040697945.2 → XP_040553879.1  lethal(3)malignant brain tumor-like protein 3 isoform X2

      UniProtKB/TrEMBL
      A0A1D5PTN3, A0A8V0XG13
      Conserved Domains (3) summary
      cd09582
      Location:738 → 803
      SAM_Scm-like-3MBT3,4; SAM domain of Scm-like-3MBT3,4 proteins of Polycomb group
      smart00561
      Location:213 → 309
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      pfam01530
      Location:535 → 563
      zf-C2HC; Zinc finger, C2HC type

    14. XM_025149093.2 → XP_025004861.1  lethal(3)malignant brain tumor-like protein 3 isoform X4

      UniProtKB/TrEMBL
      A0A8V0XML3
      Conserved Domains (3) summary
      cd09582
      Location:605 → 670
      SAM_Scm-like-3MBT3,4; SAM domain of Scm-like-3MBT3,4 proteins of Polycomb group
      smart00561
      Location:80 → 176
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      pfam01530
      Location:402 → 430
      zf-C2HC; Zinc finger, C2HC type

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052575.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      57462124..57540341 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046915294.1 → XP_046771250.1  lethal(3)malignant brain tumor-like protein 3 isoform X3

      UniProtKB/TrEMBL
      A0A8V0XML3

    2. XM_040667451.2 → XP_040523385.1  lethal(3)malignant brain tumor-like protein 3 isoform X2

      UniProtKB/TrEMBL
      A0A1D5PTN3, A0A8V0XG13
      Conserved Domains (3) summary
      cd09582
      Location:738 → 803
      SAM_Scm-like-3MBT3,4; SAM domain of Scm-like-3MBT3,4 proteins of Polycomb group
      smart00561
      Location:213 → 309
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      pfam01530
      Location:535 → 563
      zf-C2HC; Zinc finger, C2HC type

    3. XM_040667459.2 → XP_040523393.1  lethal(3)malignant brain tumor-like protein 3 isoform X2

      UniProtKB/TrEMBL
      A0A1D5PTN3, A0A8V0XG13
      Conserved Domains (3) summary
      cd09582
      Location:738 → 803
      SAM_Scm-like-3MBT3,4; SAM domain of Scm-like-3MBT3,4 proteins of Polycomb group
      smart00561
      Location:213 → 309
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      pfam01530
      Location:535 → 563
      zf-C2HC; Zinc finger, C2HC type

    4. XM_040667456.2 → XP_040523390.1  lethal(3)malignant brain tumor-like protein 3 isoform X2

      UniProtKB/TrEMBL
      A0A1D5PTN3, A0A8V0XG13
      Conserved Domains (3) summary
      cd09582
      Location:738 → 803
      SAM_Scm-like-3MBT3,4; SAM domain of Scm-like-3MBT3,4 proteins of Polycomb group
      smart00561
      Location:213 → 309
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      pfam01530
      Location:535 → 563
      zf-C2HC; Zinc finger, C2HC type

    5. XM_040667455.2 → XP_040523389.1  lethal(3)malignant brain tumor-like protein 3 isoform X2

      UniProtKB/TrEMBL
      A0A1D5PTN3, A0A8V0XG13
      Conserved Domains (3) summary
      cd09582
      Location:738 → 803
      SAM_Scm-like-3MBT3,4; SAM domain of Scm-like-3MBT3,4 proteins of Polycomb group
      smart00561
      Location:213 → 309
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      pfam01530
      Location:535 → 563
      zf-C2HC; Zinc finger, C2HC type

    6. XM_046915293.1 → XP_046771249.1  lethal(3)malignant brain tumor-like protein 3 isoform X2

      UniProtKB/TrEMBL
      A0A1D5PTN3, A0A8V0XG13

    7. XM_040667457.2 → XP_040523391.1  lethal(3)malignant brain tumor-like protein 3 isoform X2

      UniProtKB/TrEMBL
      A0A1D5PTN3, A0A8V0XG13
      Conserved Domains (3) summary
      cd09582
      Location:738 → 803
      SAM_Scm-like-3MBT3,4; SAM domain of Scm-like-3MBT3,4 proteins of Polycomb group
      smart00561
      Location:213 → 309
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      pfam01530
      Location:535 → 563
      zf-C2HC; Zinc finger, C2HC type

    8. XM_040667452.2 → XP_040523386.1  lethal(3)malignant brain tumor-like protein 3 isoform X2

      UniProtKB/TrEMBL
      A0A1D5PTN3, A0A8V0XG13
      Conserved Domains (3) summary
      cd09582
      Location:738 → 803
      SAM_Scm-like-3MBT3,4; SAM domain of Scm-like-3MBT3,4 proteins of Polycomb group
      smart00561
      Location:213 → 309
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      pfam01530
      Location:535 → 563
      zf-C2HC; Zinc finger, C2HC type

    9. XM_040667453.2 → XP_040523387.1  lethal(3)malignant brain tumor-like protein 3 isoform X2

      UniProtKB/TrEMBL
      A0A1D5PTN3, A0A8V0XG13
      Conserved Domains (3) summary
      cd09582
      Location:738 → 803
      SAM_Scm-like-3MBT3,4; SAM domain of Scm-like-3MBT3,4 proteins of Polycomb group
      smart00561
      Location:213 → 309
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      pfam01530
      Location:535 → 563
      zf-C2HC; Zinc finger, C2HC type

    10. XM_040667454.2 → XP_040523388.1  lethal(3)malignant brain tumor-like protein 3 isoform X2

      UniProtKB/TrEMBL
      A0A1D5PTN3, A0A8V0XG13
      Conserved Domains (3) summary
      cd09582
      Location:738 → 803
      SAM_Scm-like-3MBT3,4; SAM domain of Scm-like-3MBT3,4 proteins of Polycomb group
      smart00561
      Location:213 → 309
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      pfam01530
      Location:535 → 563
      zf-C2HC; Zinc finger, C2HC type

    11. XM_040667450.2 → XP_040523384.1  lethal(3)malignant brain tumor-like protein 3 isoform X1

      UniProtKB/TrEMBL
      A0A8V0XG13
      Conserved Domains (2) summary
      cd09582
      Location:786 → 851
      SAM_Scm-like-3MBT3,4; SAM domain of Scm-like-3MBT3,4 proteins of Polycomb group
      smart00561
      Location:261 → 357
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2

    12. XM_046915292.1 → XP_046771248.1  lethal(3)malignant brain tumor-like protein 3 isoform X2

      UniProtKB/TrEMBL
      A0A1D5PTN3, A0A8V0XG13

    13. XM_040667458.2 → XP_040523392.1  lethal(3)malignant brain tumor-like protein 3 isoform X2

      UniProtKB/TrEMBL
      A0A1D5PTN3, A0A8V0XG13
      Conserved Domains (3) summary
      cd09582
      Location:738 → 803
      SAM_Scm-like-3MBT3,4; SAM domain of Scm-like-3MBT3,4 proteins of Polycomb group
      smart00561
      Location:213 → 309
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      pfam01530
      Location:535 → 563
      zf-C2HC; Zinc finger, C2HC type

    14. XM_040667460.1 → XP_040523394.1  lethal(3)malignant brain tumor-like protein 3 isoform X4

      UniProtKB/TrEMBL
      A0A8V0XML3
      Conserved Domains (3) summary
      cd09582
      Location:605 → 670
      SAM_Scm-like-3MBT3,4; SAM domain of Scm-like-3MBT3,4 proteins of Polycomb group
      smart00561
      Location:80 → 176
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      pfam01530
      Location:402 → 430
      zf-C2HC; Zinc finger, C2HC type
    Nucleotide Protein Strain
    Heading Accession and Version

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