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    ST8SIA6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 [ Gallus gallus (chicken) ]

    Gene ID: 414335, updated on 3-Dec-2024

    Summary

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    Official Symbol
    ST8SIA6provided by CGNC
    Official Full Name
    ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6provided by CGNC
    Primary source
    CGNC:6583
    See related
    Ensembl:ENSGALG00010004172
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    SIAT8F
    Orthologs
    human mouse all
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    Genomic context

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    See ST8SIA6 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 2 NC_052533.1 (19623277..19686829)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 2 NC_052574.1 (19653005..19716560)

    Chromosome 2 - NC_052533.1Genomic Context describing neighboring genes Neighboring gene signal transducing adaptor molecule Neighboring gene 3-hydroxyacyl-CoA dehydratase 1 Neighboring gene uncharacterized LOC124417728 Neighboring gene microRNA 1661 Neighboring gene vimentin

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The animal sialyltransferases and sialyltransferase-related genes: a phylogenetic approach. Harduin-Lepers A, et al. Glycobiology, 2005 Aug. PMID 15843597
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in N-glycan processing IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in oligosaccharide metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein glycosylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    alpha-2,8-sialyltransferase 8F
    NP_001383496.1
    NP_001383497.1
    XP_046766530.1
    XP_046766531.1
    XP_046766532.1
    XP_046766533.1
    XP_046766535.1
    XP_046775538.1
    XP_046775540.1
    XP_046775542.1
    XP_046775545.1
    XP_046775546.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001396567.1 → NP_001383496.1  alpha-2,8-sialyltransferase 8F precursor

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000036
      UniProtKB/TrEMBL
      A0A1D5PEI3, A0A8V0XIW3

    2. NM_001396568.1 → NP_001383497.1  alpha-2,8-sialyltransferase 8F precursor

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000036
      UniProtKB/TrEMBL
      A0A1D5PEI3, A0A8V0XIW3
      Related
      ENSGALP00010005700.1, ENSGALT00010009735.1

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052533.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      19623277..19686829
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046919589.1 → XP_046775545.1  alpha-2,8-sialyltransferase 8F isoform X4

      UniProtKB/TrEMBL
      A0A8V0XIW3

    2. XM_046919590.1 → XP_046775546.1  alpha-2,8-sialyltransferase 8F isoform X5

    3. XM_046919586.1 → XP_046775542.1  alpha-2,8-sialyltransferase 8F isoform X3

      UniProtKB/TrEMBL
      A0A8V0XIW3

    4. XM_046919584.1 → XP_046775540.1  alpha-2,8-sialyltransferase 8F isoform X2

      UniProtKB/TrEMBL
      A0A8V0XIW3, A0A8V0XNA7
      Related
      ENSGALP00010005701.1, ENSGALT00010009738.1

    5. XM_046919582.1 → XP_046775538.1  alpha-2,8-sialyltransferase 8F isoform X1

      UniProtKB/TrEMBL
      A0A8V0XG67, A0A8V0XIW3
      Related
      ENSGALP00010005699.1, ENSGALT00010009732.1

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052574.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      19653005..19716560
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046910577.1 → XP_046766533.1  alpha-2,8-sialyltransferase 8F isoform X4

      UniProtKB/TrEMBL
      A0A8V0XIW3

    2. XM_046910579.1 → XP_046766535.1  alpha-2,8-sialyltransferase 8F isoform X5

    3. XM_046910576.1 → XP_046766532.1  alpha-2,8-sialyltransferase 8F isoform X3

      UniProtKB/TrEMBL
      A0A8V0XIW3

    4. XM_046910575.1 → XP_046766531.1  alpha-2,8-sialyltransferase 8F isoform X2

      UniProtKB/TrEMBL
      A0A8V0XIW3, A0A8V0XNA7

    5. XM_046910574.1 → XP_046766530.1  alpha-2,8-sialyltransferase 8F isoform X1

      UniProtKB/TrEMBL
      A0A8V0XIW3

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001001603.1: Suppressed sequence

      Description
      NM_001001603.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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