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    UHRF2 ubiquitin like with PHD and ring finger domains 2 [ Gallus gallus (chicken) ]

    Gene ID: 431601, updated on 3-Dec-2024

    Summary

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    Symbol
    UHRF2provided by CGNC
    Full Name
    ubiquitin like with PHD and ring finger domains 2provided by CGNC
    Primary source
    CGNC:11194
    See related
    Ensembl:ENSGALG00010012965
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See UHRF2 in Genome Data Viewer
    Location:
    chromosome: Z
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) Z NC_052572.1 (28361207..28443545)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) Z NC_059536.1 (28361207..28443545)

    Chromosome Z - NC_052572.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121108622 Neighboring gene bromodomain containing 10 Neighboring gene uncharacterized LOC100858941 Neighboring gene translation initiation factor IF-2-like Neighboring gene glycine decarboxylase Neighboring gene lysine demethylase 4C

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. UHRF genes regulate programmed interdigital tissue regression and chondrogenesis in the embryonic limb. Sanchez-Fernandez C, et al. Cell Death Dis, 2019 Apr 25. PMID 31024001, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ubiquitin protein ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of gene expression via chromosomal CpG island methylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    E3 ubiquitin-protein ligase UHRF2
    Names
    ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase
    ubiquitin-like, containing PHD and RING finger domains, 2
    XP_003643050.1
    XP_004949134.1
    XP_040512516.1
    XP_046791684.1
    XP_046791685.1
    XP_046791686.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052572.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      28361207..28443545
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_004949077.5 → XP_004949134.1  E3 ubiquitin-protein ligase UHRF2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0YBF6, A0A8V0YPN2
      Related
      ENSGALP00010018109.1, ENSGALT00010031115.1
      Conserved Domains (6) summary
      cd01797
      Location:1 → 78
      NIRF_N; amino-terminal ubiquitin-like domain of Np95 and NIRF
      smart00184
      Location:747 → 785
      RING; Ring finger
      smart00213
      Location:3 → 74
      UBQ; Ubiquitin homologues
      cd15617
      Location:350 → 396
      PHD_UHRF2; PHD finger found in ubiquitin-like PHD and RING finger domain-containing protein 2 (UHRF2)
      pfam02182
      Location:450 → 617
      SAD_SRA; SAD/SRA domain
      pfam12148
      Location:129 → 316
      TTD; Tandem tudor domain within UHRF1

    2. XM_003643002.6 → XP_003643050.1  E3 ubiquitin-protein ligase UHRF2 isoform X2

      UniProtKB/TrEMBL
      A0A8V0YBF6
      Related
      ENSGALP00010018103.1, ENSGALT00010031109.1
      Conserved Domains (6) summary
      cd01797
      Location:1 → 78
      NIRF_N; amino-terminal ubiquitin-like domain of Np95 and NIRF
      smart00184
      Location:746 → 784
      RING; Ring finger
      smart00213
      Location:3 → 74
      UBQ; Ubiquitin homologues
      cd15617
      Location:350 → 396
      PHD_UHRF2; PHD finger found in ubiquitin-like PHD and RING finger domain-containing protein 2 (UHRF2)
      pfam02182
      Location:450 → 617
      SAD_SRA; SAD/SRA domain
      pfam12148
      Location:129 → 316
      TTD; Tandem tudor domain within UHRF1

    3. XM_040656582.2 → XP_040512516.1  E3 ubiquitin-protein ligase UHRF2 isoform X3

      UniProtKB/TrEMBL
      A0A8V0YBF6
      Conserved Domains (3) summary
      cd15617
      Location:266 → 312
      PHD_UHRF2; PHD finger found in ubiquitin-like PHD and RING finger domain-containing protein 2 (UHRF2)
      cd16613
      Location:661 → 706
      RING-HC_UHRF; RING finger, HC subclass, found in ubiquitin-like PHD and RING finger domain-containing proteins, UHRF1 and UHRF2, and similar proteins
      cl02620
      Location:363 → 533
      SAD_SRA; SAD/SRA domain

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_059536.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      28361207..28443545
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046935728.1 → XP_046791684.1  E3 ubiquitin-protein ligase UHRF2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0YBF6, A0A8V0YPN2

    2. XM_046935729.1 → XP_046791685.1  E3 ubiquitin-protein ligase UHRF2 isoform X2

      UniProtKB/TrEMBL
      A0A8V0YBF6

    3. XM_046935730.1 → XP_046791686.1  E3 ubiquitin-protein ligase UHRF2 isoform X3

      UniProtKB/TrEMBL
      A0A8V0YBF6
    Nucleotide Protein Strain
    Heading Accession and Version

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