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    MEF2C myocyte enhancer factor 2C [ Gallus gallus (chicken) ]

    Gene ID: 769007, updated on 17-Aug-2024

    Summary

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    Symbol
    MEF2Cprovided by CGNC
    Full Name
    myocyte enhancer factor 2Cprovided by CGNC
    Primary source
    CGNC:10854
    See related
    Ensembl:ENSGALG00010007430
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See MEF2C in Genome Data Viewer
    Location:
    chromosome: Z
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) Z NC_052572.1 (61121809..61259046)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) Z NC_059536.1 (61121809..61259046)

    Chromosome Z - NC_052572.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121108463 Neighboring gene centrin 3 Neighboring gene uncharacterized LOC101752071 Neighboring gene uncharacterized LOC124417517 Neighboring gene uncharacterized LOC101752151 Neighboring gene uncharacterized LOC100859691

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cell-type homologies and the origins of the neocortex. Dugas-Ford J, et al. Proc Natl Acad Sci U S A, 2012 Oct 16. PMID 23027930, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables histone deacetylase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein dimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in heart development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    myocyte-specific enhancer factor 2C
    Names
    MADS box transcription enhancer factor 2, polypeptide C (myocyte enhancer factor 2C)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052572.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      61121809..61259046
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046905690.1 → XP_046761646.1  myocyte-specific enhancer factor 2C isoform X1

    2. XM_025144791.3 → XP_025000559.1  myocyte-specific enhancer factor 2C isoform X3

      Conserved Domains (2) summary
      cd00265
      Location:2 → 78
      MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
      pfam12347
      Location:107 → 152
      HJURP_C; Holliday junction regulator protein family C-terminal repeat

    3. XM_025144794.3 → XP_025000562.1  myocyte-specific enhancer factor 2C isoform X6

      UniProtKB/TrEMBL
      A0A1D5P4J1
      Related
      ENSGALP00010009793.1, ENSGALT00010017717.1
      Conserved Domains (2) summary
      COG5068
      Location:1 → 245
      ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
      cd00265
      Location:2 → 78
      MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...

    4. XM_040655952.2 → XP_040511886.1  myocyte-specific enhancer factor 2C isoform X4

      UniProtKB/TrEMBL
      A0A1D5PNH4
      Conserved Domains (2) summary
      cd00265
      Location:2 → 78
      MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
      pfam12347
      Location:97 → 150
      HJURP_C; Holliday junction regulator protein family C-terminal repeat

    5. XM_046905691.1 → XP_046761647.1  myocyte-specific enhancer factor 2C isoform X3

    6. XM_040655947.2 → XP_040511881.1  myocyte-specific enhancer factor 2C isoform X3

      Related
      ENSGALP00010009791.1, ENSGALT00010017711.1
      Conserved Domains (2) summary
      cd00265
      Location:2 → 78
      MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
      pfam12347
      Location:107 → 152
      HJURP_C; Holliday junction regulator protein family C-terminal repeat

    7. XM_040655941.2 → XP_040511875.1  myocyte-specific enhancer factor 2C isoform X2

      Conserved Domains (3) summary
      COG5068
      Location:1 → 263
      ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
      cd00265
      Location:2 → 78
      MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
      pfam12347
      Location:117 → 170
      HJURP_C; Holliday junction regulator protein family C-terminal repeat

    8. XM_040655958.2 → XP_040511892.1  myocyte-specific enhancer factor 2C isoform X5

      UniProtKB/TrEMBL
      A0A8V0XXN3
      Related
      ENSGALP00010009790.1, ENSGALT00010017710.1
      Conserved Domains (2) summary
      COG5068
      Location:1 → 263
      ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
      cd00265
      Location:2 → 78
      MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...

    9. XM_040655951.2 → XP_040511885.1  myocyte-specific enhancer factor 2C isoform X4

      UniProtKB/TrEMBL
      A0A1D5PNH4
      Related
      ENSGALP00010009792.1, ENSGALT00010017714.1
      Conserved Domains (2) summary
      cd00265
      Location:2 → 78
      MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
      pfam12347
      Location:97 → 150
      HJURP_C; Holliday junction regulator protein family C-terminal repeat

    10. XM_040655959.2 → XP_040511893.1  myocyte-specific enhancer factor 2C isoform X7

      Conserved Domains (2) summary
      cd00265
      Location:2 → 78
      MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
      pfam12347
      Location:97 → 153
      HJURP_C; Holliday junction regulator protein family C-terminal repeat

    11. XM_040655948.2 → XP_040511882.1  myocyte-specific enhancer factor 2C isoform X3

      Conserved Domains (2) summary
      cd00265
      Location:2 → 78
      MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
      pfam12347
      Location:107 → 152
      HJURP_C; Holliday junction regulator protein family C-terminal repeat

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_059536.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      61121809..61259046
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046936955.1 → XP_046792911.1  myocyte-specific enhancer factor 2C isoform X1

    2. XM_046936958.1 → XP_046792914.1  myocyte-specific enhancer factor 2C isoform X3

    3. XM_046936964.1 → XP_046792920.1  myocyte-specific enhancer factor 2C isoform X6

      UniProtKB/TrEMBL
      A0A1D5P4J1

    4. XM_046936962.1 → XP_046792918.1  myocyte-specific enhancer factor 2C isoform X4

      UniProtKB/TrEMBL
      A0A1D5PNH4

    5. XM_046936960.1 → XP_046792916.1  myocyte-specific enhancer factor 2C isoform X3

    6. XM_046936957.1 → XP_046792913.1  myocyte-specific enhancer factor 2C isoform X3

    7. XM_046936956.1 → XP_046792912.1  myocyte-specific enhancer factor 2C isoform X2

    8. XM_046936963.1 → XP_046792919.1  myocyte-specific enhancer factor 2C isoform X5

      UniProtKB/TrEMBL
      A0A8V0XXN3

    9. XM_046936961.1 → XP_046792917.1  myocyte-specific enhancer factor 2C isoform X4

      UniProtKB/TrEMBL
      A0A1D5PNH4

    10. XM_046936965.1 → XP_046792921.1  myocyte-specific enhancer factor 2C isoform X7

      Conserved Domains (2) summary
      cd00265
      Location:2 → 78
      MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
      pfam12347
      Location:97 → 153
      HJURP_C; Holliday junction regulator protein family C-terminal repeat

    11. XM_046936959.1 → XP_046792915.1  myocyte-specific enhancer factor 2C isoform X3

    Nucleotide Protein Strain
    Heading Accession and Version

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