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    DIS3L2 DIS3 like 3'-5' exoribonuclease 2 [ Gallus gallus (chicken) ]

    Gene ID: 424934, updated on 3-Dec-2024

    Summary

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    Symbol
    DIS3L2provided by CGNC
    Full Name
    DIS3 like 3'-5' exoribonuclease 2provided by CGNC
    Primary source
    CGNC:5872
    See related
    Ensembl:ENSGALG00010017657
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See DIS3L2 in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    26
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 9 NC_052540.1 (15098132..15262055)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 9 NC_052581.1 (14891696..15055633)

    Chromosome 9 - NC_052540.1Genomic Context describing neighboring genes Neighboring gene COP9 signalosome subunit 7B Neighboring gene natriuretic peptide C Neighboring gene alkaline phosphatase, intestinal like Neighboring gene alkaline phosphatase, intestinal

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 3'-5'-RNA exonuclease activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in miRNA catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in P-body IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of exosome (RNase complex) IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    DIS3-like exonuclease 2
    Names
    DIS3 mitotic control homolog (S. cerevisiae)-like 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052540.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      15098132..15262055
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046898826.1 → XP_046754782.1  DIS3-like exonuclease 2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0Z263, A0A8V0Z2M1

    2. XM_015291462.4 → XP_015146948.3  DIS3-like exonuclease 2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0Z263, A0A8V0Z2M1
      Related
      ENSGALP00010025169.1, ENSGALT00010042679.1
      Conserved Domains (2) summary
      COG0557
      Location:493 → 1075
      VacB; Exoribonuclease R [Transcription]
      pfam17216
      Location:311 → 502
      Rrp44_CSD1; Rrp44-like cold shock domain

    3. XM_025153427.3 → XP_025009195.2  DIS3-like exonuclease 2 isoform X3

      UniProtKB/TrEMBL
      A0A8V0Z2L6, A0A8V0Z9M6
      Related
      ENSGALP00010025166.1, ENSGALT00010042676.1
      Conserved Domains (2) summary
      COG0557
      Location:227 → 809
      VacB; Exoribonuclease R [Transcription]
      pfam17216
      Location:45 → 236
      Rrp44_CSD1; Rrp44-like cold shock domain

    4. XM_025153425.3 → XP_025009193.2  DIS3-like exonuclease 2 isoform X2

      UniProtKB/TrEMBL
      A0A8V0Z263
      Conserved Domains (2) summary
      COG0557
      Location:493 → 937
      VacB; Exoribonuclease R [Transcription]
      pfam17216
      Location:311 → 502
      Rrp44_CSD1; Rrp44-like cold shock domain

    5. XM_046898825.1 → XP_046754781.1  DIS3-like exonuclease 2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0Z263, A0A8V0Z2M1

    6. XM_025153426.3 → XP_025009194.2  DIS3-like exonuclease 2 isoform X3

      UniProtKB/TrEMBL
      A0A8V0Z2L6, A0A8V0Z9M6
      Conserved Domains (2) summary
      COG0557
      Location:227 → 809
      VacB; Exoribonuclease R [Transcription]
      pfam17216
      Location:45 → 236
      Rrp44_CSD1; Rrp44-like cold shock domain

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052581.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      14891696..15055633
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046924367.1 → XP_046780323.1  DIS3-like exonuclease 2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0Z263

    2. XM_040678718.2 → XP_040534652.1  DIS3-like exonuclease 2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0Z263
      Conserved Domains (2) summary
      COG0557
      Location:493 → 1075
      VacB; Exoribonuclease R [Transcription]
      pfam17216
      Location:311 → 502
      Rrp44_CSD1; Rrp44-like cold shock domain

    3. XM_040678720.2 → XP_040534654.1  DIS3-like exonuclease 2 isoform X3

      UniProtKB/TrEMBL
      A0A8V0Z2L6, A0A8V0Z9M6
      Conserved Domains (2) summary
      COG0557
      Location:227 → 809
      VacB; Exoribonuclease R [Transcription]
      pfam17216
      Location:45 → 236
      Rrp44_CSD1; Rrp44-like cold shock domain

    4. XM_040678719.2 → XP_040534653.1  DIS3-like exonuclease 2 isoform X2

      UniProtKB/TrEMBL
      A0A8V0Z263
      Conserved Domains (2) summary
      COG0557
      Location:493 → 937
      VacB; Exoribonuclease R [Transcription]
      pfam17216
      Location:311 → 502
      Rrp44_CSD1; Rrp44-like cold shock domain

    5. XM_046924366.1 → XP_046780322.1  DIS3-like exonuclease 2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0Z263

    6. XM_040678721.2 → XP_040534655.1  DIS3-like exonuclease 2 isoform X3

      UniProtKB/TrEMBL
      A0A8V0Z2L6, A0A8V0Z9M6
      Conserved Domains (2) summary
      COG0557
      Location:227 → 809
      VacB; Exoribonuclease R [Transcription]
      pfam17216
      Location:45 → 236
      Rrp44_CSD1; Rrp44-like cold shock domain
    Nucleotide Protein
    Heading Accession and Version

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