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    HOOK3 hook microtubule tethering protein 3 [ Gallus gallus (chicken) ]

    Gene ID: 427297, updated on 3-Dec-2024

    Summary

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    Symbol
    HOOK3provided by CGNC
    Full Name
    hook microtubule tethering protein 3provided by CGNC
    Primary source
    CGNC:11464
    See related
    Ensembl:ENSGALG00010012011
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See HOOK3 in Genome Data Viewer
    Location:
    chromosome: Z
    Exon count:
    26
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) Z NC_052572.1 (54381250..54459922)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) Z NC_059536.1 (54381250..54459922)

    Chromosome Z - NC_052572.1Genomic Context describing neighboring genes Neighboring gene transcription factor AP-1-like Neighboring gene THAP domain containing 1 Neighboring gene ring finger protein 170 Neighboring gene potassium channel modulatory factor 1 Neighboring gene farnesyltransferase, CAAX box, alpha Neighboring gene fucosyltransferase 10

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables dynein light intermediate chain binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables microtubule binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cytoplasmic microtubule organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cytoskeleton-dependent intracellular transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in centrosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein Hook homolog 3
    Names
    hook homolog 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052572.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      54381250..54459922
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046905620.1 → XP_046761576.1  protein Hook homolog 3 isoform X7

      UniProtKB/TrEMBL
      A0A8V0Y797
      Related
      ENSGALP00010016544.1, ENSGALT00010028756.1

    2. XM_040655803.2 → XP_040511737.1  protein Hook homolog 3 isoform X6

      UniProtKB/TrEMBL
      A0A8V0YDG7
      Conserved Domains (2) summary
      TIGR02168
      Location:234 → 553
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      TIGR02169
      Location:116 → 333
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

    3. XM_003643039.6 → XP_003643087.2  protein Hook homolog 3 isoform X1

      UniProtKB/TrEMBL
      A0A8V0Y7B7, A0A8V0YFQ0
      Related
      ENSGALP00010016564.1, ENSGALT00010028789.1
      Conserved Domains (2) summary
      pfam05622
      Location:12 → 712
      HOOK; HOOK protein
      cl23717
      Location:274 → 322
      crotonase-like; Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. ...

    4. XM_015280495.4 → XP_015135981.1  protein Hook homolog 3 isoform X3

      UniProtKB/TrEMBL
      A0A8V0YFQ0
      Conserved Domains (2) summary
      pfam05622
      Location:12 → 710
      HOOK; HOOK protein
      cl23717
      Location:274 → 322
      crotonase-like; Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. ...

    5. XM_004949342.5 → XP_004949399.1  protein Hook homolog 3 isoform X2

      UniProtKB/TrEMBL
      A0A8V0YFQ0
      Related
      ENSGALP00010016562.1, ENSGALT00010028785.1
      Conserved Domains (2) summary
      pfam05622
      Location:12 → 710
      HOOK; HOOK protein
      cl23717
      Location:274 → 322
      crotonase-like; Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. ...

    6. XM_015280498.4 → XP_015135984.1  protein Hook homolog 3 isoform X4

      UniProtKB/TrEMBL
      A0A8V0YFQ0
      Conserved Domains (3) summary
      pfam05622
      Location:12 → 675
      HOOK; HOOK protein
      pfam08286
      Location:448 → 513
      Spc24; Spc24 subunit of Ndc80
      cl23717
      Location:274 → 322
      crotonase-like; Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. ...

    7. XM_040655801.2 → XP_040511735.1  protein Hook homolog 3 isoform X5

      UniProtKB/TrEMBL
      A0A8V0YC86, A0A8V0YFQ0
      Related
      ENSGALP00010016568.1, ENSGALT00010028794.1
      Conserved Domains (1) summary
      PRK03918
      Location:130 → 626
      PRK03918; DNA double-strand break repair ATPase Rad50

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_059536.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      54381250..54459922
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046936890.1 → XP_046792846.1  protein Hook homolog 3 isoform X7

      UniProtKB/TrEMBL
      A0A8V0Y797

    2. XM_046936889.1 → XP_046792845.1  protein Hook homolog 3 isoform X6

      UniProtKB/TrEMBL
      A0A8V0YDG7

    3. XM_046936884.1 → XP_046792840.1  protein Hook homolog 3 isoform X1

      UniProtKB/TrEMBL
      A0A8V0Y7B7, A0A8V0YFQ0

    4. XM_046936886.1 → XP_046792842.1  protein Hook homolog 3 isoform X3

      UniProtKB/TrEMBL
      A0A8V0YFQ0

    5. XM_046936885.1 → XP_046792841.1  protein Hook homolog 3 isoform X2

      UniProtKB/TrEMBL
      A0A8V0YFQ0

    6. XM_046936887.1 → XP_046792843.1  protein Hook homolog 3 isoform X4

      UniProtKB/TrEMBL
      A0A8V0YFQ0

    7. XM_046936888.1 → XP_046792844.1  protein Hook homolog 3 isoform X5

      UniProtKB/TrEMBL
      A0A8V0YC86, A0A8V0YFQ0
    Nucleotide Protein Strain
    Heading Accession and Version

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