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    ST3GAL3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 [ Homo sapiens (human) ]

    Gene ID: 6487, updated on 10-Dec-2024

    Summary

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    Official Symbol
    ST3GAL3provided by HGNC
    Official Full Name
    ST3 beta-galactoside alpha-2,3-sialyltransferase 3provided by HGNC
    Primary source
    HGNC:HGNC:10866
    See related
    Ensembl:ENSG00000126091 MIM:606494; AllianceGenome:HGNC:10866
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    ST3N; DEE15; MRT12; SIAT6; EIEE15; ST3GALII; ST3GalIII; ST3Gal III
    Summary
    The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein is normally found in the Golgi apparatus but can be proteolytically processed to a soluble form. This protein is a member of glycosyltransferase family 29. Mutations in this gene have been associated with a form of autosomal recessive nonsymdromic cognitive disability as well as infantile epileptic encephalopathy. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2017]
    Expression
    Broad expression in testis (RPKM 4.7), fat (RPKM 2.9) and 25 other tissues See more
    Orthologs
    mouse all
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    Genomic context

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    See ST3GAL3 in Genome Data Viewer
    Location:
    1p34.1
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (43707536..43931159)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (43578028..43802236)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (44173207..44396831)

    Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124904165 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 920 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 921 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr1:44131983-44133182 Neighboring gene ReSE screen-validated silencer GRCh37_chr1:44142744-44142920 Neighboring gene lysine demethylase 4A Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:44172642-44173159 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 790 Neighboring gene KDM4A antisense RNA 1 Neighboring gene ST3GAL3 antisense RNA 1 Neighboring gene uncharacterized LOC124904721 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 923 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 924 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr1:44232560-44233095 Neighboring gene uncharacterized LOC124904166 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 791 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr1:44287043-44288242 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:44299839-44300606 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:44300607-44301374 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:44306354-44307342 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:44307343-44308331 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:44323792-44324410 Neighboring gene microRNA 6079 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 925 Neighboring gene SHMT1 pseudogene 1 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:44336631-44337131 Neighboring gene Sharpr-MPRA regulatory region 749 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:44365355-44366213 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:44379389-44380204 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:44386271-44387086 Neighboring gene Sharpr-MPRA regulatory region 11119 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 926 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:44397735-44398235 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 927 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 792 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 793 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:44401004-44401598 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:44401599-44402193 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 795 Neighboring gene long intergenic non-protein coding RNA 2918 Neighboring gene artemin

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Characterization of the promoter region of the human Galbeta1,3(4)GlcNAc alpha2,3-sialyltransferase III (hST3Gal III) gene. Taniguchi A, et al. Biochim Biophys Acta, 2003 Apr 15. PMID 12697334
    2. Localization of Golgi-resident glycosyltransferases. Tu L, et al. Cell Mol Life Sci, 2010 Jan. PMID 19727557, Free PMC Article
    3. Identification of seven new alpha2,3-sialyltransferase III, ST3Gal III, transcripts from human foetal brain. Grahn A, et al. Glycoconj J, 2004. PMID 15316282
    4. ST3GAL3 mutations impair the development of higher cognitive functions. Hu H, et al. Am J Hum Genet, 2011 Sep 9. PMID 21907012, Free PMC Article
    5. West syndrome caused by ST3Gal-III deficiency. Edvardson S, et al. Epilepsia, 2013 Feb. PMID 23252400

    See all (43) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Human ST3Gal II and ST6GalNAc IV genes increase human serum-mediated cytotoxicity to xenogeneic cells.
      Title: Human ST3Gal II and ST6GalNAc IV genes increase human serum-mediated cytotoxicity to xenogeneic cells.
    2. The epilepsy phenotype of ST3GAL3-related developmental and epileptic encephalopathy.
      Title: The epilepsy phenotype of ST3GAL3-related developmental and epileptic encephalopathy.
    3. ST3GAL3 Promotes the Inflammatory Response of Fibroblast-Like Synoviocytes in Rheumatoid Arthritis by Activating the TLR9/MyD88 Pathway.
      Title: ST3GAL3 Promotes the Inflammatory Response of Fibroblast-Like Synoviocytes in Rheumatoid Arthritis by Activating the TLR9/MyD88 Pathway.
    4. A novel variant of ST3GAL3 causes non-syndromic autosomal recessive intellectual disability in Iranian patients.
      Title: A novel variant of ST3GAL3 causes non-syndromic autosomal recessive intellectual disability in Iranian patients.
    5. A novel nonsense and inactivating variant of ST3GAL3 in two infant siblings suffering severe epilepsy and expressing circulating CA19.9.
      Title: A novel nonsense and inactivating variant of ST3GAL3 in two infant siblings suffering severe epilepsy and expressing circulating CA19.9.
    6. ST3GAL3 is associated with ADHD risk.
      Title: Contribution of Intellectual Disability-Related Genes to ADHD Risk and to Locomotor Activity in Drosophila.
    7. these were increased in the ST3GAL3 KO and ST3GAL6 KO cells, whereas the alpha2,3-sialylation levels of EGFR were significantly decreased in the ST3GAL6 KO cells
      Title: ST3GAL3, ST3GAL4, and ST3GAL6 differ in their regulation of biological functions via the specificities for the α2,3-sialylation of target proteins.
    8. Silencing of ST3Gal3 by small interfering RNA reversed these effects and increased the protein levels of caspase8/3, which may contribute to paclitaxelinduced apoptosis. The results of the present study suggested that ST3Gal3 was a target for paclitaxel-related resistance during ovarian cancer chemotherapy.
      Title: ST3Gal3 confers paclitaxel‑mediated chemoresistance in ovarian cancer cells by attenuating caspase‑8/3 signaling.
    9. Data show that endometrial tissues at secretory phase expressed a 4-fold higher ST3 beta-galactoside alpha-2,3-sialyltransferase 3 protein (ST3Gal3) level relative to the tissues at proliferative phase.
      Title: The sialyltransferase ST3Gal3 facilitates the receptivity of the uterine endometrium in vitro and in vivo.
    10. CA19.9 appears as a physiological product whose synthesis strongly depends on the tissue specific and epigenetically-regulated expression of B3GALT5 and ST3GAL3.
      Title: Unexpected distribution of CA19.9 and other type 1 chain Lewis antigens in normal and cancer tissues of colon and pancreas: Importance of the detection method and role of glycosyltransferase regulation.
    Submit: New GeneRIF Correction See all GeneRIFs (20)

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    Associated conditions

    Description Tests
    Developmental and epileptic encephalopathy, 15
    MedGen: C3554316 OMIM: 615006 GeneReviews: Not available
    		Compare labs
    Intellectual disability, autosomal recessive 12
    MedGen: C1970200 OMIM: 611090 GeneReviews: Not available
    		Compare labs

    EBI GWAS Catalog

    Description
    A genome-wide association study of aging.
    EBI GWAS Catalog
    Age of onset of amyotrophic lateral sclerosis is modulated by a locus on 1p34.1.
    EBI GWAS Catalog

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    HIV-1 interactions

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    Replication interactions

    Interaction Pubs
    Knockdown of ST3 beta-galactoside alpha-2,3-sialyltransferase 3 (ST3GAL3) by siRNA inhibits the early stages of HIV-1 replication in 293T cells infected with VSV-G pseudotyped HIV-1 PubMed

    Protein interactions

    Protein Gene Interaction Pubs
    Envelope surface glycoprotein gp160, precursor env Oligosaccharide side-chains of HIV-1 gp160 are processed by glycosidase I and II, mannosidase I and II, acetylglucosaminyl transferase I and II, and fucosyl, galactosyl and sialyl transferases in both the endoplasmic reticulum and golgi apparatus PubMed

    Go to the HIV-1, Human Interaction Database

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables N-acetyllactosaminide alpha-2,3-sialyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables beta-galactoside (CMP) alpha-2,3-sialyltransferase activity TAS
    Traceable Author Statement
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables sialyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables sialyltransferase activity TAS
    Traceable Author Statement
    more info
    		  
    Process Evidence Code Pubs
    involved_in O-glycan processing TAS
    Traceable Author Statement
    more info
    		  
    involved_in ganglioside biosynthetic process via lactosylceramide IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in glycosphingolipid biosynthetic process TAS
    Traceable Author Statement
    more info
    		  
    involved_in keratan sulfate biosynthetic process TAS
    Traceable Author Statement
    more info
    		  
    involved_in oligosaccharide biosynthetic process TAS
    Traceable Author Statement
    more info
    		  
    involved_in protein glycosylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in viral protein processing TAS
    Traceable Author Statement
    more info
    		  
    Component Evidence Code Pubs
    located_in Golgi cisterna membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in Golgi membrane TAS
    Traceable Author Statement
    more info
    		  
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase
    Names
    Gal beta-1,3(4)GlcNAc alpha-2,3 sialyltransferase
    alpha 2,3-ST 3
    alpha 2,3-sialyltransferase III
    alpha-2,3-sialyltransferase II
    sialyltransferase 6 (N-acetyllacosaminide alpha 2,3-sialyltransferase)
    sialyltransferase 6 (N-acetyllactosaminide alpha 2,3-sialyltransferase)
    NP_001257388.1
    NP_001257389.1
    NP_001257390.1
    NP_001257391.1
    NP_001257392.1
    NP_001257393.1
    NP_001257394.1
    NP_001257395.1
    NP_001337548.1
    NP_001337549.1
    NP_001337550.1
    NP_001350502.1
    NP_001397710.1
    NP_006270.1
    NP_777623.2
    NP_777624.1
    NP_777625.1
    NP_777626.1
    NP_777627.1
    NP_777628.2
    NP_777629.1
    NP_777630.1
    NP_777631.2
    XP_011540275.1
    XP_011540276.1
    XP_011540278.1
    XP_011540282.1
    XP_011540283.1
    XP_011540286.1
    XP_011540287.1
    XP_011540288.1
    XP_011540290.1
    XP_016857602.1
    XP_016857605.1
    XP_047284140.1
    XP_047284141.1
    XP_047284155.1
    XP_047284156.1
    XP_047284157.1
    XP_047284177.1
    XP_047284188.1
    XP_047284192.1
    XP_047284217.1
    XP_047284221.1
    XP_047284226.1
    XP_047284229.1
    XP_047284230.1
    XP_047284232.1
    XP_047284236.1
    XP_047284238.1
    XP_054194292.1
    XP_054194293.1
    XP_054194294.1
    XP_054194295.1
    XP_054194296.1
    XP_054194297.1
    XP_054194298.1
    XP_054194299.1
    XP_054194300.1
    XP_054194301.1
    XP_054194302.1
    XP_054194303.1
    XP_054194304.1
    XP_054194305.1
    XP_054194306.1
    XP_054194307.1
    XP_054194308.1
    XP_054194309.1
    XP_054194310.1
    XP_054194311.1
    XP_054194312.1
    XP_054194313.1
    XP_054194314.1
    XP_054194315.1
    XP_054194316.1

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_028196.2 RefSeqGene

      Range
      5002..228625
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001270459.2 → NP_001257388.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform k

      See identical proteins and their annotated locations for NP_001257388.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (11) lacks an alternate in-frame exon, uses an alternate in-frame splice site in the 5' coding region, and uses an alternate in-frame splice site in the 3' coding region compared to variant 1. The resulting isoforom (k, also called B1-90) is shorter compared to isoform a.
      Source sequence(s)
      AA478788, AF425854, AL357079, AL451062
      Consensus CDS
      CCDS57988.1
      UniProtKB/TrEMBL
      Q96L53
      Related
      ENSP00000361444.1, ENST00000372369.5
      Conserved Domains (1) summary
      pfam00777
      Location:126 → 341
      Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

    2. NM_001270460.2 → NP_001257389.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform l

      See identical proteins and their annotated locations for NP_001257389.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (12) lacks an alternate in-frame exon and uses an alternate in-frame splice site in the 5' coding region compared to variant 1. The resulting isoform (l, also called B4+173) is shorter compared to isoform a.
      Source sequence(s)
      AA478788, AF425855, AL357079, AL451062
      Consensus CDS
      CCDS57989.1
      UniProtKB/TrEMBL
      A0A2U3TZH9
      Related
      ENSP00000361449.2, ENST00000372374.7
      Conserved Domains (1) summary
      pfam00777
      Location:95 → 340
      Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

    3. NM_001270461.3 → NP_001257390.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform m

      See identical proteins and their annotated locations for NP_001257390.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (13) uses an alternate in-frame splice site in the 5' coding region and lacks four alternate in-frame exons compared to variant 1. The resulting isoform (m, also called C4) is shorter compared to isoform a.
      Source sequence(s)
      AA478788, AL357079, AY167993, DR003980, HY013772
      Consensus CDS
      CCDS57990.1
      UniProtKB/TrEMBL
      A0A2R8YFA0
      Related
      ENSP00000494146.1, ENST00000642934.1
      Conserved Domains (1) summary
      pfam00777
      Location:91 → 247
      Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

    4. NM_001270462.3 → NP_001257391.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform n

      See identical proteins and their annotated locations for NP_001257391.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (14) uses an alternate in-frame splice site in the 5' coding region, lacks five alternate in-frame exons compared to variant 1. The resulting isoform (n, also called C11) is shorter compared to isoform a.
      Source sequence(s)
      AA478788, AL357079, AY167997, DR003980, HY013772
      Consensus CDS
      CCDS85964.1
      UniProtKB/Swiss-Prot
      Q11203
      Related
      ENSP00000432682.2, ENST00000531993.6
      Conserved Domains (1) summary
      pfam00777
      Location:60 → 216
      Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

    5. NM_001270463.3 → NP_001257392.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform o

      See identical proteins and their annotated locations for NP_001257392.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (15) lacks five alternate in-frame exons compared to variant 1. The resulting isoform (o, also called D5) is shorter compared to isoform a.
      Source sequence(s)
      AA478788, AL357079, AY167994, DR003980, HY013772
      Consensus CDS
      CCDS57993.1
      UniProtKB/TrEMBL
      A0A2R8YF05
      Related
      ENSP00000361442.1, ENST00000372367.5
      Conserved Domains (1) summary
      pfam00777
      Location:106 → 183
      Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

    6. NM_001270464.3 → NP_001257393.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform p

      See identical proteins and their annotated locations for NP_001257393.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (16) uses an alternate in-frame splice site in the 5' coding region and lacks five alternate in-frame exon compared to variant 1. The resulting isoform (p, also called C5) is shorter compared to isoform a.
      Source sequence(s)
      AA478788, AL357079, AY167995, DR003980, HY013772
      Consensus CDS
      CCDS57991.1
      UniProtKB/TrEMBL
      A0A2R8YE42
      Related
      ENSP00000434876.1, ENST00000528371.5
      Conserved Domains (1) summary
      pfam00777
      Location:91 → 168
      Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

    7. NM_001270465.3 → NP_001257394.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform q

      See identical proteins and their annotated locations for NP_001257394.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (17) lacks two alternate in-frame exons, uses an alternate splice site which results in a frameshift and lacks an exon in the 3' coding region compared to variant 1. The resulting isoform (q, also called D2+26) has a shorter and distinct C-terminus compared to isoform a.
      Source sequence(s)
      AA478788, AF425863, AL357079, DR003980, HY013772
      Consensus CDS
      CCDS57994.1
      UniProtKB/TrEMBL
      A0A2R8YF05
      Related
      ENSP00000335633.7, ENST00000335430.10
      Conserved Domains (1) summary
      pfam00777
      Location:125 → 185
      Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

    8. NM_001270466.3 → NP_001257395.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform r

      See identical proteins and their annotated locations for NP_001257395.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (18) uses an alternate in-frame splice site in the 5' coding region and lacks eight alternate in-frame exons compared to variant 1. The resulting isoform (r, also called C12) is shorter compared to isoform a.
      Source sequence(s)
      AA478788, AL357079, AL592548, AY167998, DR003980, HY013772
      Consensus CDS
      CCDS57992.1
      UniProtKB/TrEMBL
      A0A2R8Y4Y4
      Related
      ENSP00000333494.3, ENST00000330208.6
      Conserved Domains (2) summary
      PRK05428
      Location:31 → 55
      PRK05428; HPr kinase/phosphorylase; Provisional
      PRK05673
      Location:53 → 83
      dnaE; DNA polymerase III subunit alpha; Validated

    9. NM_001350619.2 → NP_001337548.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform s

      Status: REVIEWED

      Source sequence(s)
      AA478788, AF425855, AL357079, BC050380, BI832120, DR003980, HY013772
      Consensus CDS
      CCDS85965.1
      UniProtKB/TrEMBL
      A0A2R8Y7D8, A0A2R8YDJ6
      Related
      ENSP00000493823.1, ENST00000642331.1
      Conserved Domains (1) summary
      pfam00777
      Location:141 → 353
      Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

    10. NM_001350620.2 → NP_001337549.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform t

      Status: REVIEWED

      Source sequence(s)
      AA478788, AF425855, AL357079, BC050380, BI832120, DN999880, HY013772
      Consensus CDS
      CCDS85962.1
      UniProtKB/TrEMBL
      A0A2R8Y6H4, A0A2R8Y7D8
      Related
      ENSP00000495333.1, ENST00000643252.1
      Conserved Domains (1) summary
      pfam00777
      Location:126 → 338
      Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

    11. NM_001350621.2 → NP_001337550.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform u

      Status: REVIEWED

      Source sequence(s)
      AA478788, AF425855, AL357079, AL521256, BC050380, BI832120, DN999880, HY013772
      Conserved Domains (1) summary
      pfam00777
      Location:33 → 245
      Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

    12. NM_001363573.2 → NP_001350502.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform v

      Status: REVIEWED

      Source sequence(s)
      AL357079, AL451062, AL592548
      Consensus CDS
      CCDS85961.1
      UniProtKB/TrEMBL
      A0A2R8Y6L4, A0A2U3TZM2
      Related
      ENSP00000495624.1, ENST00000647237.1
      Conserved Domains (1) summary
      pfam00777
      Location:180 → 318
      Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

    13. NM_001410781.1 → NP_001397710.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform w

      Status: REVIEWED

      Source sequence(s)
      AL357079, AL451062, AL592548
      Consensus CDS
      CCDS90936.1
      UniProtKB/TrEMBL
      A0A2R8Y732, A0A2R8Y7D8
      Related
      ENSP00000495683.1, ENST00000646686.1

    14. NM_006279.5 → NP_006270.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform j

      See identical proteins and their annotated locations for NP_006270.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (10) has multiple differences in the coding region but maintains the reading frame compared to variant 1. The resulting isoform (j, also called B1) is shorter compared to isoform a.
      Source sequence(s)
      AA478788, BC050380, HY013772
      Consensus CDS
      CCDS492.1
      UniProtKB/Swiss-Prot
      A9Z1W2, D3DPX8, Q11203, Q5T4W9, Q5T4X0, Q5T4X7, Q5T4X8, Q5T4X9, Q5T4Y0, Q5T4Y2, Q5T4Y3, Q5T4Y4, Q86UR6, Q86UR7, Q86UR8, Q86UR9, Q86US0, Q86US1, Q86US2, Q8IX41, Q8IX42, Q8IX43, Q8IX44, Q8IX45, Q8IX46, Q8IX47, Q8IX48, Q8IX49, Q8IX50, Q8IX51, Q8IX52, Q8IX53, Q8IX54, Q8IX55, Q8IX56, Q8IX57, Q8IX58
      UniProtKB/TrEMBL
      Q96L53
      Related
      ENSP00000317192.6, ENST00000347631.8
      Conserved Domains (1) summary
      pfam00777
      Location:107 → 371
      Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

    15. NM_174963.5 → NP_777623.2  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform a

      See identical proteins and their annotated locations for NP_777623.2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a, also called A8).
      Source sequence(s)
      AF425853, AK301829, AL357079, BC050380, HY013772
      Consensus CDS
      CCDS493.1
      UniProtKB/TrEMBL
      A0A1B2JLU4
      Related
      ENSP00000262915.3, ENST00000262915.8
      Conserved Domains (1) summary
      pfam00777
      Location:195 → 440
      Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

    16. NM_174964.4 → NP_777624.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform b

      See identical proteins and their annotated locations for NP_777624.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1, resulting in an isoform (b, also called A1) that is shorter compared to isoform a.
      Source sequence(s)
      AA478788, AF425851, AL357079, DR003980, HY013772
      Consensus CDS
      CCDS494.1
      UniProtKB/TrEMBL
      Q96L53
      Related
      ENSP00000355341.5, ENST00000361392.9
      Conserved Domains (1) summary
      pfam00777
      Location:122 → 386
      Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

    17. NM_174965.4 → NP_777625.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform c

      See identical proteins and their annotated locations for NP_777625.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3) has multiple differences in the coding region, one of which results in a frameshift compared to variant 1. The resulting isoform (c, also called A7) has a distinct C-terminus and is shorter compared to isoform a.
      Source sequence(s)
      AA478788, AF425852, AL357079, DR003980, HY013772
      Consensus CDS
      CCDS499.1
      UniProtKB/TrEMBL
      A0A2R8YDA9
      Related
      ENSP00000439634.1, ENST00000545417.5

    18. NM_174966.4 → NP_777626.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform d

      See identical proteins and their annotated locations for NP_777626.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (4) has multiple differences in the coding region but maintains the reading frame compared to variant 1. The resulting isoform (d, also called B4) is shorter compared to isoform a.
      Source sequence(s)
      AA478788, AF425856, AL357079, DR003980, HY013772
      Consensus CDS
      CCDS495.1
      UniProtKB/TrEMBL
      A0A2R8YFA0
      Related
      ENSP00000330463.3, ENST00000353126.8
      Conserved Domains (1) summary
      pfam00777
      Location:107 → 263
      Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

    19. NM_174967.4 → NP_777627.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform e

      See identical proteins and their annotated locations for NP_777627.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (5) has multiple differences in the coding region, one of which results in a frameshift compared to variant 1. The resulting isoform (e, also called B7) has a distinct C-terminus and is shorter compared to isoform a.
      Source sequence(s)
      AA478788, AF425857, AL357079, DR003980, HY013772
      Consensus CDS
      CCDS500.1
      UniProtKB/TrEMBL
      A0A2R8Y6U3
      Related
      ENSP00000361437.2, ENST00000372362.6

    20. NM_174968.5 → NP_777628.2  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform f

      See identical proteins and their annotated locations for NP_777628.2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (6) utilizes an alternate in-frame splice site compared to variant 1, resulting in an isoform (f, also called B8) that is shorter compared to isoform a.
      Source sequence(s)
      AF425858, AK301829, AL357079, BC050380, HY013772
      Consensus CDS
      CCDS496.1
      UniProtKB/TrEMBL
      A0A1B2JLU4
      Related
      ENSP00000316999.6, ENST00000351035.8
      Conserved Domains (1) summary
      pfam00777
      Location:180 → 425
      Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

    21. NM_174969.4 → NP_777629.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform g

      See identical proteins and their annotated locations for NP_777629.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (7) has multiple differences in the coding region but maintains the reading frame compared to variant 1. The resulting isoform (g, also called C1) is shorter compared to isoform a.
      Source sequence(s)
      AA478788, AF425859, AL357079, DR003980, HY013772
      Consensus CDS
      CCDS497.1
      UniProtKB/TrEMBL
      Q96L53
      Related
      ENSP00000354748.4, ENST00000361400.9
      Conserved Domains (1) summary
      pfam00777
      Location:91 → 355
      Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

    22. NM_174970.4 → NP_777630.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform h

      See identical proteins and their annotated locations for NP_777630.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (8) has multiple differences in the coding region, one of which results in a frameshift compared to variant 1. The resulting isoform (h, also called C7) has a distinct C-terminus and is shorter compared to isoform a.
      Source sequence(s)
      AA478788, AF425860, AL357079, DR003980, HY013772
      Consensus CDS
      CCDS53310.1
      UniProtKB/TrEMBL
      A0A2R8Y6U3
      Related
      ENSP00000435603.1, ENST00000531451.5

    23. NM_174971.5 → NP_777631.2  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform i

      See identical proteins and their annotated locations for NP_777631.2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (9) lacks an alternate in-frame segment compared to variant 1, resulting in an isoform (i, also called C8) that is shorter compared to isoform a.
      Source sequence(s)
      AF425861, AK301829, AL357079, BC050380, HY013772
      Consensus CDS
      CCDS498.1
      UniProtKB/TrEMBL
      A0A1B2JLU4
      Related
      ENSP00000361447.2, ENST00000372372.7
      Conserved Domains (1) summary
      pfam00777
      Location:164 → 409
      Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

    RNA

    1. NR_073016.3 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (19) uses an alternate splice site in an internal exon compared to variant 1. This variant is represented as non-coding because the use of the 5'-most supported translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AA478788, AF425864, AL357079, DR003980, HY013772
      Related
      ENST00000642949.1

    2. NR_073017.3 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (20) lacks three alternate internal exons compared to variant 1. This variant is represented as non-coding because the use of the 5'-most supported translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AA478788, AF425868, AL357079, DR003980, HY013772
      Related
      ENST00000646027.1

    3. NR_073018.3 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (21) contains an alternate internal exon compared to variant 1. This variant is represented as non-coding because the use of the 5'-most supported translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AA478788, AF425865, AL357079, AL592548, DR003980, HY013772
      Related
      ENST00000643597.1

    4. NR_073019.3 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (22) lacks alternate internal exons compared to variant 1. This variant is represented as non-coding because the use of the 5'-most supported translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AA478788, AF425869, AL357079, DR003980, HY013772

    5. NR_073020.3 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (23) lacks an alternate internal exon compared to variant 1. This variant is represented as non-coding because the use of the 5'-most supported translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AA478788, AL357079, AL592548, AY167996, DR003980, HY013772

    6. NR_073021.3 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (24) contains an alternate internal exon compared to variant 1. This variant is represented as non-coding because the use of the 5'-most supported translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AA478788, AF425867, AL357079, DR003980, HY013772

    7. NR_073023.3 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (25) lacks three alternate internal exons compared to variant 1. This variant is represented as non-coding because the use of the 5'-most supported translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AA478788, AL357079, AL451062, AY167992, DR003980, HY013772
      Related
      ENST00000642194.1

    8. NR_146867.2 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AA478788, AF425855, AL357079, BC050380, BI822816, DN999880, HY013772
      Related
      ENST00000645142.1

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

      Range
      43707536..43931159
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047428200.1 → XP_047284156.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X5

      UniProtKB/TrEMBL
      A0A2R8Y6H4, A0A2R8Y7D8

    2. XM_047428221.1 → XP_047284177.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X8

      UniProtKB/Swiss-Prot
      A9Z1W2, D3DPX8, Q11203, Q5T4W9, Q5T4X0, Q5T4X7, Q5T4X8, Q5T4X9, Q5T4Y0, Q5T4Y2, Q5T4Y3, Q5T4Y4, Q86UR6, Q86UR7, Q86UR8, Q86UR9, Q86US0, Q86US1, Q86US2, Q8IX41, Q8IX42, Q8IX43, Q8IX44, Q8IX45, Q8IX46, Q8IX47, Q8IX48, Q8IX49, Q8IX50, Q8IX51, Q8IX52, Q8IX53, Q8IX54, Q8IX55, Q8IX56, Q8IX57, Q8IX58
      UniProtKB/TrEMBL
      Q96L53

    3. XM_047428184.1 → XP_047284140.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X1

      UniProtKB/TrEMBL
      A0A2R8Y7D8

    4. XM_011541981.3 → XP_011540283.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X10

      UniProtKB/TrEMBL
      A0A2U3TZM2
      Conserved Domains (1) summary
      pfam00777
      Location:176 → 335
      Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

    5. XM_047428270.1 → XP_047284226.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X14

      UniProtKB/TrEMBL
      A0A2R8YFA0
      Related
      ENSP00000496289.1, ENST00000644922.1

    6. XM_011541974.3 → XP_011540276.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X3

      UniProtKB/TrEMBL
      A0A2R8Y7D8
      Conserved Domains (1) summary
      pfam00777
      Location:161 → 404
      Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

    7. XM_011541976.3 → XP_011540278.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X4

      UniProtKB/TrEMBL
      A0A2R8Y7D8
      Conserved Domains (1) summary
      pfam00777
      Location:145 → 388
      Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

    8. XM_011541973.3 → XP_011540275.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X2

      UniProtKB/TrEMBL
      A0A2R8Y7Z2
      Conserved Domains (1) summary
      pfam00777
      Location:176 → 419
      Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

    9. XM_011541986.4 → XP_011540288.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X12

      See identical proteins and their annotated locations for XP_011540288.1

      Conserved Domains (1) summary
      pfam00777
      Location:176 → 317
      Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

    10. XM_011541985.3 → XP_011540287.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X12

      See identical proteins and their annotated locations for XP_011540287.1

      Conserved Domains (1) summary
      pfam00777
      Location:176 → 317
      Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

    11. XM_011541984.3 → XP_011540286.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X12

      See identical proteins and their annotated locations for XP_011540286.1

      Conserved Domains (1) summary
      pfam00777
      Location:176 → 317
      Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

    12. XM_047428274.1 → XP_047284230.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X15

      UniProtKB/TrEMBL
      A0A2R8YFA0

    13. XM_047428276.1 → XP_047284232.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X16

      UniProtKB/TrEMBL
      A0A2R8YFA0

    14. XM_047428280.1 → XP_047284236.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X17

    15. XM_047428185.1 → XP_047284141.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X1

      UniProtKB/TrEMBL
      A0A2R8Y7D8

    16. XM_047428273.1 → XP_047284229.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X14

      UniProtKB/TrEMBL
      A0A2R8YFA0

    17. XM_047428232.1 → XP_047284188.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X9

      UniProtKB/TrEMBL
      Q96L53

    18. XM_047428199.1 → XP_047284155.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X5

      UniProtKB/TrEMBL
      A0A2R8Y6H4, A0A2R8Y7D8

    19. XM_017002113.2 → XP_016857602.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X8

      UniProtKB/Swiss-Prot
      A9Z1W2, D3DPX8, Q11203, Q5T4W9, Q5T4X0, Q5T4X7, Q5T4X8, Q5T4X9, Q5T4Y0, Q5T4Y2, Q5T4Y3, Q5T4Y4, Q86UR6, Q86UR7, Q86UR8, Q86UR9, Q86US0, Q86US1, Q86US2, Q8IX41, Q8IX42, Q8IX43, Q8IX44, Q8IX45, Q8IX46, Q8IX47, Q8IX48, Q8IX49, Q8IX50, Q8IX51, Q8IX52, Q8IX53, Q8IX54, Q8IX55, Q8IX56, Q8IX57, Q8IX58
      UniProtKB/TrEMBL
      Q96L53
      Related
      ENSP00000494201.1, ENST00000644195.1
      Conserved Domains (1) summary
      pfam00777
      Location:107 → 371
      Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

    20. XM_047428201.1 → XP_047284157.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X6

      UniProtKB/TrEMBL
      A0A2R8Y7D8

    21. XM_047428236.1 → XP_047284192.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X11

    22. XM_017002116.2 → XP_016857605.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X11

      Conserved Domains (1) summary
      pfam00777
      Location:13 → 256
      Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

    23. XM_047428265.1 → XP_047284221.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X6

      UniProtKB/TrEMBL
      A0A2R8Y7D8

    24. XM_047428282.1 → XP_047284238.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X11

    25. XM_011541980.4 → XP_011540282.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X7

      UniProtKB/TrEMBL
      A0A2R8Y7D8
      Conserved Domains (1) summary
      pfam00777
      Location:52 → 295
      Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

    26. XM_047428261.1 → XP_047284217.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X13

    27. XM_011541988.3 → XP_011540290.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X13

      See identical proteins and their annotated locations for XP_011540290.1

      Conserved Domains (1) summary
      pfam00777
      Location:1 → 243
      Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

    RNA

    1. XR_946744.3 RNA Sequence

    2. XR_946743.3 RNA Sequence

    3. XR_007063036.1 RNA Sequence

    4. XR_946742.3 RNA Sequence

    5. XR_007063037.1 RNA Sequence

    6. XR_007063040.1 RNA Sequence

    7. XR_007063042.1 RNA Sequence

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060925.1 Alternate T2T-CHM13v2.0

      Range
      43578028..43802236
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054338317.1 → XP_054194292.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X1

      UniProtKB/TrEMBL
      A0A2R8Y7D8

    2. XM_054338327.1 → XP_054194302.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X10

      UniProtKB/TrEMBL
      A0A2U3TZM2

    3. XM_054338336.1 → XP_054194311.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X14

      UniProtKB/TrEMBL
      A0A2R8YFA0

    4. XM_054338320.1 → XP_054194295.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X3

      UniProtKB/TrEMBL
      A0A2R8Y7D8

    5. XM_054338321.1 → XP_054194296.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X4

      UniProtKB/TrEMBL
      A0A2R8Y7D8

    6. XM_054338319.1 → XP_054194294.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X2

      UniProtKB/TrEMBL
      A0A2R8Y7Z2

    7. XM_054338332.1 → XP_054194307.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X12

    8. XM_054338331.1 → XP_054194306.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X12

    9. XM_054338338.1 → XP_054194313.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X15

      UniProtKB/TrEMBL
      A0A2R8YFA0

    10. XM_054338339.1 → XP_054194314.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X16

      UniProtKB/TrEMBL
      A0A2R8YFA0

    11. XM_054338330.1 → XP_054194305.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X12

    12. XM_054338340.1 → XP_054194315.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X17

    13. XM_054338325.1 → XP_054194300.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X8

      UniProtKB/Swiss-Prot
      A9Z1W2, D3DPX8, Q11203, Q5T4W9, Q5T4X0, Q5T4X7, Q5T4X8, Q5T4X9, Q5T4Y0, Q5T4Y2, Q5T4Y3, Q5T4Y4, Q86UR6, Q86UR7, Q86UR8, Q86UR9, Q86US0, Q86US1, Q86US2, Q8IX41, Q8IX42, Q8IX43, Q8IX44, Q8IX45, Q8IX46, Q8IX47, Q8IX48, Q8IX49, Q8IX50, Q8IX51, Q8IX52, Q8IX53, Q8IX54, Q8IX55, Q8IX56, Q8IX57, Q8IX58
      UniProtKB/TrEMBL
      Q96L53

    14. XM_054338324.1 → XP_054194299.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X8

      UniProtKB/Swiss-Prot
      A9Z1W2, D3DPX8, Q11203, Q5T4W9, Q5T4X0, Q5T4X7, Q5T4X8, Q5T4X9, Q5T4Y0, Q5T4Y2, Q5T4Y3, Q5T4Y4, Q86UR6, Q86UR7, Q86UR8, Q86UR9, Q86US0, Q86US1, Q86US2, Q8IX41, Q8IX42, Q8IX43, Q8IX44, Q8IX45, Q8IX46, Q8IX47, Q8IX48, Q8IX49, Q8IX50, Q8IX51, Q8IX52, Q8IX53, Q8IX54, Q8IX55, Q8IX56, Q8IX57, Q8IX58
      UniProtKB/TrEMBL
      Q96L53

    15. XM_054338318.1 → XP_054194293.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X1

      UniProtKB/TrEMBL
      A0A2R8Y7D8

    16. XM_054338337.1 → XP_054194312.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X14

      UniProtKB/TrEMBL
      A0A2R8YFA0

    17. XM_054338322.1 → XP_054194297.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X5

      UniProtKB/TrEMBL
      A0A2R8Y6H4, A0A2R8Y7D8

    18. XM_054338326.1 → XP_054194301.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X9

      UniProtKB/TrEMBL
      Q96L53

    19. XM_054338328.1 → XP_054194303.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X11

    20. XM_054338329.1 → XP_054194304.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X11

    21. XM_054338335.1 → XP_054194310.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X6

      UniProtKB/TrEMBL
      A0A2R8Y7D8

    22. XM_054338341.1 → XP_054194316.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X11

    23. XM_054338323.1 → XP_054194298.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X7

      UniProtKB/TrEMBL
      A0A2R8Y7D8

    24. XM_054338333.1 → XP_054194308.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X13

    25. XM_054338334.1 → XP_054194309.1  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X13

    RNA

    1. XR_008486147.1 RNA Sequence

    2. XR_008486146.1 RNA Sequence

    3. XR_008486144.1 RNA Sequence

    4. XR_008486145.1 RNA Sequence

    5. XR_008486148.1 RNA Sequence

    6. XR_008486149.1 RNA Sequence

    7. XR_008486150.1 RNA Sequence

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_174972.1: Suppressed sequence

      Description
      NM_174972.1: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q11203.1 GenPept UniProtKB/Swiss-Prot:Q11203

    Gene LinkOut

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