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    ASF2 Asf2p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 851330, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ASF2
    Official Full Name
    Asf2p
    Primary source
    SGD:S000002356
    Locus tag
    YDL197C
    See related
    AllianceGenome:SGD:S000002356; FungiDB:YDL197C; VEuPathDB:YDL197C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in silent mating-type cassette heterochromatin formation. Located in chromosome, telomeric region and nucleus. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ASF2 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    1
    Sequence:
    Chromosome: IV; NC_001136.10 (104917..106494, complement)

    Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Ggc1p Neighboring gene Sec31p Neighboring gene glucose sensor

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001136.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Two new S-phase-specific genes from Saccharomyces cerevisiae. Le S, et al. Yeast, 1997 Sep 15. PMID 9290207
    2. Sir3-nucleosome interactions in spreading of silent chromatin in Saccharomyces cerevisiae. Buchberger JR, et al. Mol Cell Biol, 2008 Nov. PMID 18794362, Free PMC Article
    3. Asf1 links Rad53 to control of chromatin assembly. Hu F, et al. Genes Dev, 2001 May 1. PMID 11331602, Free PMC Article
    4. Localization of proteins that are coordinately expressed with Cln2 during the cell cycle. Sundin BA, et al. Yeast, 2004 Jul 15. PMID 15282802
    5. Cotranscriptional recruitment of the pseudouridylsynthetase Cbf5p and of the RNA binding protein Naf1p during H/ACA snoRNP assembly. Yang PK, et al. Mol Cell Biol, 2005 Apr. PMID 15798213, Free PMC Article

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in silent mating-type cassette heterochromatin formation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chromosome, telomeric region IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus HDA PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Asf2p
    NP_010084.1
    • Anti-silencing protein; causes derepression of silent loci when overexpressed

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001136.10 Reference assembly

      Range
      104917..106494 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180257.1 → NP_010084.1  TPA: Asf2p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_010084.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VRF7, P32448
      UniProtKB/TrEMBL
      B5VF80, N1P6Q5
      Conserved Domains (1) summary
      COG1196
      Location:38 → 328
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P32448.1

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