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    TAF8 Taf8p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854926, updated on 9-Dec-2024

    Summary

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    Official Symbol
    TAF8
    Official Full Name
    Taf8p
    Primary source
    SGD:S000004582
    Locus tag
    YML114C
    See related
    AllianceGenome:SGD:S000004582; FungiDB:YML114C; VEuPathDB:YML114C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    TAF65
    Summary
    Predicted to contribute to RNA polymerase II general transcription initiation factor activity. Involved in transcription by RNA polymerase II. Located in nucleus. Part of transcription factor TFIID complex. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See TAF8 in Genome Data Viewer
    Location:
    chromosome: XIII
    Exon count:
    1
    Sequence:
    Chromosome: XIII; NC_001145.3 (42043..43575, complement)

    Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene borate transporter Neighboring gene Van1p Neighboring gene Dat1p Neighboring gene Ctk3p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001145.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Taf2 mediates DNA binding of Taf14. Klein BJ, et al. Nat Commun, 2022 Jun 8. PMID 35676274, Free PMC Article
    2. The C Terminus of the RNA Polymerase II Transcription Factor IID (TFIID) Subunit Taf2 Mediates Stable Association of Subunit Taf14 into the Yeast TFIID Complex. Feigerle JT, et al. J Biol Chem, 2016 Oct 21. PMID 27587401, Free PMC Article
    3. Genome-wide transcriptional dependence on TAF1 functional domains. Irvin JD, et al. J Biol Chem, 2006 Mar 10. PMID 16407318
    4. Histone folds mediate selective heterodimerization of yeast TAF(II)25 with TFIID components yTAF(II)47 and yTAF(II)65 and with SAGA component ySPT7. Gangloff YG, et al. Mol Cell Biol, 2001 Mar. PMID 11238921, Free PMC Article
    5. Protein-protein interaction map for yeast TFIID. Yatherajam G, et al. Nucleic Acids Res, 2003 Feb 15. PMID 12582245, Free PMC Article

    See all (54) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. the Ccr4-Not complex independently controls TFIID promoter distribution and Msn2-dependent trans-activation through a process involving a Glc7/Bud14 phosphatase
      Title: The Ccr4-Not complex independently controls both Msn2-dependent transcriptional activation--via a newly identified Glc7/Bud14 type I protein phosphatase module--and TFIID promoter distribution.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    contributes_to RNA polymerase II general transcription initiation factor activity IC
    Inferred by Curator
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in transcription by RNA polymerase II IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus HDA PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of transcription factor TFIID complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of transcription factor TFIID complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of transcription factor TFIID complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Taf8p
    NP_013593.1
    • TFIID subunit (65 kDa); involved in RNA polymerase II transcription initiation

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001145.3 Reference assembly

      Range
      42043..43575 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182476.1 → NP_013593.1  TPA: Taf8p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013593.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W0H0, Q03750
      UniProtKB/TrEMBL
      B3LLE5, C7GV96, G2WJU2, N1NX77
      Conserved Domains (1) summary
      cd08049
      Location:175 → 226
      TAF8; TATA Binding Protein (TBP) Associated Factor 8
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q03750.1

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