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    Slc37a1 solute carrier family 37 member 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 294321, updated on 9-Dec-2024

    Summary

    Symbol
    Slc37a1provided by RGD
    Full Name
    solute carrier family 37 member 1provided by RGD
    Primary source
    RGD:1308587
    See related
    EnsemblRapid:ENSRNOG00000001169 AllianceGenome:RGD:1308587
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable glucose 6-phosphate:phosphate antiporter activity. Predicted to be involved in glucose-6-phosphate transport and phosphate ion transmembrane transport. Predicted to be active in endoplasmic reticulum membrane. Orthologous to human SLC37A1 (solute carrier family 37 member 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Heart (RPKM 46.8), Kidney (RPKM 36.5) and 9 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Slc37a1 in Genome Data Viewer
    Location:
    20p12
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 20 NC_086038.1 (9361733..9435227)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 20 NC_051355.1 (9360501..9433895)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 20 NC_005119.4 (10026839..10087691)

    Chromosome 20 - NC_086038.1Genomic Context describing neighboring genes Neighboring gene transmembrane serine protease 3 Neighboring gene ubiquitin associated and SH3 domain containing, A Neighboring gene uncharacterized LOC120098980 Neighboring gene radial spoke head component 1 Neighboring gene uncharacterized LOC120098916 Neighboring gene phosphodiesterase 9A

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables glucose 6-phosphate:phosphate antiporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables glucose 6-phosphate:phosphate antiporter activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in glucose-6-phosphate transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in glucose-6-phosphate transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in phosphate ion transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in phosphate ion transmembrane transport ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in endoplasmic reticulum membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    glucose-6-phosphate exchanger SLC37A1
    Names
    glycerol-3-phosphate transporter
    solute carrier family 37 (glucose-6-phosphate transporter), member 1
    solute carrier family 37 (glycerol-3-phosphate transporter), member 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001011944.2NP_001011944.1  glucose-6-phosphate exchanger SLC37A1

      See identical proteins and their annotated locations for NP_001011944.1

      Status: VALIDATED

      Source sequence(s)
      BC081990
      UniProtKB/TrEMBL
      A6JJZ4, Q66H72
      Related
      ENSRNOP00000001544.5, ENSRNOT00000001544.7
      Conserved Domains (1) summary
      cd17344
      Location:21520
      MFS_SLC37A1_2; Solute carrier family 37 members 1 and 2 of the Major Facilitator Superfamily of transporters

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086038.1 Reference GRCr8

      Range
      9361733..9435227
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039098542.2XP_038954470.1  glucose-6-phosphate exchanger SLC37A1 isoform X1

      UniProtKB/TrEMBL
      A6JJZ4, Q66H72
      Conserved Domains (1) summary
      cd17344
      Location:21520
      MFS_SLC37A1_2; Solute carrier family 37 members 1 and 2 of the Major Facilitator Superfamily of transporters
    2. XM_017601594.3XP_017457083.1  glucose-6-phosphate exchanger SLC37A1 isoform X1

      UniProtKB/TrEMBL
      A6JJZ4, Q66H72
      Conserved Domains (1) summary
      cd17344
      Location:21520
      MFS_SLC37A1_2; Solute carrier family 37 members 1 and 2 of the Major Facilitator Superfamily of transporters
    3. XM_017601595.3XP_017457084.1  glucose-6-phosphate exchanger SLC37A1 isoform X1

      UniProtKB/TrEMBL
      A6JJZ4, Q66H72
      Conserved Domains (1) summary
      cd17344
      Location:21520
      MFS_SLC37A1_2; Solute carrier family 37 members 1 and 2 of the Major Facilitator Superfamily of transporters
    4. XM_039098543.2XP_038954471.1  glucose-6-phosphate exchanger SLC37A1 isoform X2

      UniProtKB/TrEMBL
      A6JJZ4
      Conserved Domains (1) summary
      cd17344
      Location:21476
      MFS_SLC37A1_2; Solute carrier family 37 members 1 and 2 of the Major Facilitator Superfamily of transporters