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    Polr1d RNA polymerase I and III subunit D [ Rattus norvegicus (Norway rat) ]

    Gene ID: 360762, updated on 9-Dec-2024

    Summary

    Official Symbol
    Polr1dprovided by RGD
    Official Full Name
    RNA polymerase I and III subunit Dprovided by RGD
    Primary source
    RGD:1564358
    See related
    AllianceGenome:RGD:1564358
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Rpo1-3
    Summary
    Predicted to enable DNA binding activity; DNA-directed 5'-3' RNA polymerase activity; and protein dimerization activity. Predicted to be involved in DNA-templated transcription. Predicted to be part of RNA polymerase I complex and RNA polymerase III complex. Human ortholog(s) of this gene implicated in Treacher Collins syndrome 2. Orthologous to human POLR1D (RNA polymerase I and III subunit D). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 231.8), Kidney (RPKM 197.6) and 9 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Polr1d in Genome Data Viewer
    Location:
    12p11
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 12 NC_086030.1 (13084505..13118069, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 12 NC_051347.1 (7970592..8004157, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 12 NC_005111.4 (9693828..9727416, complement)

    Chromosome 12 - NC_086030.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120095852 Neighboring gene GS homeobox 1 Neighboring gene ligand of numb-protein X 2 Neighboring gene uncharacterized LOC120095885 Neighboring gene uncharacterized LOC120095884

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Clone Names

    • MGC112727

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables DNA-directed 5'-3' RNA polymerase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein dimerization activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of RNA polymerase I complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of RNA polymerase III complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    DNA-directed RNA polymerases I and III subunit RPAC2
    Names
    RNA polymerase 1-3
    RNA polymerase I subunit D
    polymerase (RNA) I polypeptide D
    polymerase (RNA) I subunit D

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001037787.1NP_001032876.1  DNA-directed RNA polymerases I and III subunit RPAC2

      See identical proteins and their annotated locations for NP_001032876.1

      Status: PROVISIONAL

      Source sequence(s)
      BC098735
      UniProtKB/TrEMBL
      A0A8I6GK67, A6K1B0, F7ELN3, Q4G058

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086030.1 Reference GRCr8

      Range
      13084505..13118069 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)