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    Syngr1 synaptogyrin 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 29205, updated on 9-Dec-2024

    Summary

    Official Symbol
    Syngr1provided by RGD
    Official Full Name
    synaptogyrin 1provided by RGD
    Primary source
    RGD:3801
    See related
    EnsemblRapid:ENSRNOG00000017108 AllianceGenome:RGD:3801
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Involved in regulated exocytosis and synaptic vesicle membrane organization. Acts upstream of or within protein targeting. Located in synaptic vesicle. Is active in synaptic vesicle membrane. Orthologous to human SYNGR1 (synaptogyrin 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 298.4), Heart (RPKM 101.0) and 9 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Syngr1 in Genome Data Viewer
    Location:
    7q34
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (113516246..113542918)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (111635911..111659341)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (121311008..121334437)

    Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene ribosomal protein L3 Neighboring gene small nucleolar RNA U82P Neighboring gene small nucleolar RNA, C/D box 43 Neighboring gene ubiquitin-conjugating enzyme E2S, pseudogene 3 Neighboring gene TGF-beta activated kinase 1/MAP3K7 binding protein 1 Neighboring gene small nucleolar RNA, H/ACA box 24

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    is_active_in Schaffer collateral - CA1 synapse ISO
    Inferred from Sequence Orthology
    more info
     
    located_in melanosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in neuromuscular junction IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in synaptic vesicle IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in synaptic vesicle membrane EXP
    Inferred from Experiment
    more info
    PubMed 
    is_active_in synaptic vesicle membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in synaptic vesicle membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in synaptic vesicle membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in terminal bouton HDA PubMed 

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_019166.2NP_062039.1  synaptogyrin-1

      See identical proteins and their annotated locations for NP_062039.1

      Status: VALIDATED

      Source sequence(s)
      CB729785, DN932005, DV724604, U39549
      UniProtKB/Swiss-Prot
      Q62876
      UniProtKB/TrEMBL
      A6HSV5
      Related
      ENSRNOP00000110355.1, ENSRNOT00000145685.1
      Conserved Domains (1) summary
      pfam01284
      Location:21167
      MARVEL; Membrane-associating domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086025.1 Reference GRCr8

      Range
      113516246..113542918
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006241971.4XP_006242033.1  synaptogyrin-1 isoform X1

      See identical proteins and their annotated locations for XP_006242033.1

      UniProtKB/TrEMBL
      A0A0U1RRP1, A6HSV6, A6HSV7
      Related
      ENSRNOP00000075756.2, ENSRNOT00000092260.3
      Conserved Domains (1) summary
      pfam01284
      Location:21167
      MARVEL; Membrane-associating domain