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    Fmc1 formation of mitochondrial complex V assembly factor 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 500087, updated on 27-Nov-2024

    Summary

    Official Symbol
    Fmc1provided by RGD
    Official Full Name
    formation of mitochondrial complex V assembly factor 1provided by RGD
    Primary source
    RGD:1559476
    See related
    EnsemblRapid:ENSRNOG00000005618 AllianceGenome:RGD:1559476
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in mitochondrial proton-transporting ATP synthase complex assembly. Predicted to act upstream of or within negative regulation of lipid catabolic process and regulation of type B pancreatic cell proliferation. Predicted to be active in mitochondrion. Orthologous to several human genes including FMC1 (formation of mitochondrial complex V assembly factor 1 homolog). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Heart (RPKM 144.0), Muscle (RPKM 130.0) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Fmc1 in Genome Data Viewer
    Location:
    4q23
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (68241009..68249045)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (67274104..67282140)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (66276835..66284868)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134486759 Neighboring gene transfer RNA arginine (anticodon CCU) 2 Neighboring gene LUC7-like 2 pre-mRNA splicing factor Neighboring gene small nuclear ribonucleoprotein E-like Neighboring gene insulin-induced gene 1 protein-like Neighboring gene killer cell lectin like receptor G2 Neighboring gene small nuclear ribonucleoprotein Sm D1-like

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General protein information

    Preferred Names
    protein FMC1 homolog
    Names
    UPF0562 protein C7orf55 homolog
    formation of mitochondrial complex V assembly factor 1 homolog
    formation of mitochondrial complexes 1 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001037795.1NP_001032884.1  protein FMC1 homolog

      See identical proteins and their annotated locations for NP_001032884.1

      Status: PROVISIONAL

      Source sequence(s)
      BC098843
      UniProtKB/Swiss-Prot
      Q4G012
      UniProtKB/TrEMBL
      A6IES4
      Related
      ENSRNOP00000007544.2, ENSRNOT00000007544.5
      Conserved Domains (1) summary
      cd20271
      Location:7103
      Complex1_LYR_FMC1; LYR (leucine-tyrosine-arginine) motif found in formation of mitochondrial complex V assembly factor 1 (FMC1) and similar proteins

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      68241009..68249045
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)