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    Taf1c TATA-box binding protein associated factor, RNA polymerase 1 subunit C [ Rattus norvegicus (Norway rat) ]

    Gene ID: 361420, updated on 27-Nov-2024

    Summary

    Official Symbol
    Taf1cprovided by RGD
    Official Full Name
    TATA-box binding protein associated factor, RNA polymerase 1 subunit Cprovided by RGD
    Primary source
    RGD:1305658
    See related
    EnsemblRapid:ENSRNOG00000015632 AllianceGenome:RGD:1305658
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable RNA polymerase I core promoter sequence-specific DNA binding activity and RNA polymerase I general transcription initiation factor activity. Predicted to be involved in RNA polymerase I preinitiation complex assembly. Predicted to be located in nucleolus and nucleoplasm. Predicted to be part of RNA polymerase transcription factor SL1 complex. Predicted to be active in fibrillar center. Orthologous to human TAF1C (TATA-box binding protein associated factor, RNA polymerase I subunit C). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Thymus (RPKM 35.0), Testes (RPKM 31.5) and 9 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Taf1c in Genome Data Viewer
    Location:
    19q12
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 19 NC_086037.1 (64561079..64567599, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 19 NC_051354.1 (47652451..47658971, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 19 NC_005118.4 (52246061..52252642, complement)

    Chromosome 19 - NC_086037.1Genomic Context describing neighboring genes Neighboring gene hydroxysteroid dehydrogenase like 1 Neighboring gene dynein, axonemal, assembly factor 1 Neighboring gene NADH:ubiquinone oxidoreductase subunit A2, pseudogene 3 Neighboring gene adenosine deaminase domain containing 2 Neighboring gene potassium voltage-gated channel modifier subfamily G member 4

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in RNA polymerase I preinitiation complex assembly IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in biological_process ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    part_of RNA polymerase transcription factor SL1 complex ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in fibrillar center IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in fibrillar center ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    TATA box-binding protein-associated factor, RNA polymerase I, subunit C
    Names
    TATA box binding protein (Tbp)-associated factor, RNA polymerase I, C
    TATA box-binding protein-associated factor 1C
    TBP-associated factor 1C
    transcription initiation factor SL1/TIF-IB subunit C

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001014155.1NP_001014177.1  TATA box-binding protein-associated factor, RNA polymerase I, subunit C

      See identical proteins and their annotated locations for NP_001014177.1

      Status: PROVISIONAL

      Source sequence(s)
      BC061804
      UniProtKB/Swiss-Prot
      Q6P773
      Related
      ENSRNOP00000020990.4, ENSRNOT00000020990.6

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086037.1 Reference GRCr8

      Range
      64561079..64567599 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063278146.1XP_063134216.1  TATA box-binding protein-associated factor, RNA polymerase I, subunit C isoform X1

    2. XM_039097872.2XP_038953800.1  TATA box-binding protein-associated factor, RNA polymerase I, subunit C isoform X1

    3. XM_039097873.2XP_038953801.1  TATA box-binding protein-associated factor, RNA polymerase I, subunit C isoform X1

    4. XM_063278147.1XP_063134217.1  TATA box-binding protein-associated factor, RNA polymerase I, subunit C isoform X1