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    Pomp proteasome maturation protein [ Rattus norvegicus (Norway rat) ]

    Gene ID: 288455, updated on 9-Dec-2024

    Summary

    Symbol
    Pompprovided by RGD
    Full Name
    proteasome maturation proteinprovided by RGD
    Primary source
    RGD:1305831
    See related
    EnsemblRapid:ENSRNOG00000049229 AllianceGenome:RGD:1305831
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1305831
    Summary
    Predicted to be involved in proteasome assembly. Predicted to be located in nuclear speck. Predicted to be active in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in proteosome-associated autoinflammatory syndrome 2. Orthologous to human POMP (proteasome maturation protein). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Heart (RPKM 1468.0), Liver (RPKM 1341.0) and 9 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Pomp in Genome Data Viewer
    Location:
    12p11
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 12 NC_086030.1 (12198262..12212132, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 12 NC_051347.1 (7162098..7174737, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 12 NC_005111.4 (8746948..8759433, complement)

    Chromosome 12 - NC_086030.1Genomic Context describing neighboring genes Neighboring gene microtubule associated scaffold protein 2 Neighboring gene U2 spliceosomal RNA Neighboring gene solute carrier family 46, member 3 Neighboring gene interferon-induced transmembrane protein 2-like Neighboring gene uncharacterized LOC102547586 Neighboring gene Fms related receptor tyrosine kinase 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in proteasome assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in proteasome assembly ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear speck ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    proteasome maturation protein
    Names
    voltage-gated potassium channel beta subunit 4.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001100942.1NP_001094412.1  proteasome maturation protein

      See identical proteins and their annotated locations for NP_001094412.1

      Status: PROVISIONAL

      Source sequence(s)
      EF535528
      UniProtKB/TrEMBL
      A0A8I6ASW7, A5HKJ3, B1WBL6
      Related
      ENSRNOP00000082440.2, ENSRNOT00000103818.2
      Conserved Domains (1) summary
      pfam05348
      Location:25138
      UMP1; Proteasome maturation factor UMP1

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086030.1 Reference GRCr8

      Range
      12198262..12212132 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063271118.1XP_063127188.1  proteasome maturation protein isoform X1