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    Rpn2 ribophorin II [ Rattus norvegicus (Norway rat) ]

    Gene ID: 64701, updated on 27-Nov-2024

    Summary

    Official Symbol
    Rpn2provided by RGD
    Official Full Name
    ribophorin IIprovided by RGD
    Primary source
    RGD:62075
    See related
    EnsemblRapid:ENSRNOG00000007492 AllianceGenome:RGD:62075
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Enables ribosome binding activity. Involved in response to xenobiotic stimulus. Located in autophagosome membrane. Orthologous to human RPN2 (ribophorin II). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Liver (RPKM 983.5), Kidney (RPKM 788.4) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Rpn2 in Genome Data Viewer
    Location:
    3q42
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (166361955..166409272)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (145941787..145989271)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (153398373..153445633)

    Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene RB transcriptional corepressor like 1 Neighboring gene 60S ribosomal protein L34 pseudogene Neighboring gene uncharacterized LOC134486195 Neighboring gene U7 small nuclear RNA Neighboring gene maestro heat-like repeat family member 8 Neighboring gene uncharacterized LOC134486194 Neighboring gene growth hormone releasing hormone Neighboring gene mannosidase beta like

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables ribosome binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in protein N-linked glycosylation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in protein N-linked glycosylation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within protein N-linked glycosylation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein N-linked glycosylation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein glycosylation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in response to xenobiotic stimulus IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in autophagosome membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear body IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nuclear body ISO
    Inferred from Sequence Orthology
    more info
     
    part_of oligosaccharyltransferase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of oligosaccharyltransferase complex IEA
    Inferred from Electronic Annotation
    more info
     
    part_of oligosaccharyltransferase complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2
    Names
    RPN-II
    dolichyl-diphosphooligosaccharide--protein glycosyltransferase 63 kDa subunit
    ribophorin-2
    NP_113886.1
    XP_006235441.1
    XP_038961743.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_031698.1NP_113886.1  dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 precursor

      See identical proteins and their annotated locations for NP_113886.1

      Status: PROVISIONAL

      Source sequence(s)
      X55298
      UniProtKB/Swiss-Prot
      P25235, Q6P9X0
      UniProtKB/TrEMBL
      A6JWR7
      Related
      ENSRNOP00000076455.1, ENSRNOT00000118622.2
      Conserved Domains (1) summary
      pfam05817
      Location:9623
      Ribophorin_II; Oligosaccharyltransferase subunit Ribophorin II

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086021.1 Reference GRCr8

      Range
      166361955..166409272
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006235379.4XP_006235441.1  dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 isoform X1

      UniProtKB/Swiss-Prot
      P25235, Q6P9X0
      UniProtKB/TrEMBL
      A0A8L2QVV5, A6JWR7
      Related
      ENSRNOP00000063207.2, ENSRNOT00000068135.4
      Conserved Domains (1) summary
      pfam05817
      Location:9623
      Ribophorin_II; Oligosaccharyltransferase subunit Ribophorin II
    2. XM_039105815.1XP_038961743.1  dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 isoform X2

      UniProtKB/TrEMBL
      A6JWR9
      Conserved Domains (1) summary
      pfam05817
      Location:2406
      Ribophorin_II; Oligosaccharyltransferase subunit Ribophorin II