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    CG4572 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 42360, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG4572provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0038738
    Locus tag
    Dmel_CG4572
    See related
    AllianceGenome:FB:FBgn0038738
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-WO02059370.13; CT14806; Dmel\CG4572
    Summary
    Enables serine hydrolase activity. Involved in dsRNA transport. Is expressed in adult head; adult heart; organism; and spermatozoon. Orthologous to human CPVL (carboxypeptidase vitellogenic like). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG4572 in Genome Data Viewer
    Location:
    92B3-92B4; 3-67 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (19862517..19864393, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (15688239..15690115, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Mitochondrial calcium uptake 3 Neighboring gene Inositol-requiring enzyme-1 Neighboring gene Mitochondrial rRNA methyltransferase 2 Neighboring gene uncharacterized protein Neighboring gene Multidrug resistance protein 5 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Viral infection impacts transposable element transcript amounts in Drosophila. Roy M, et al. Proc Natl Acad Sci U S A, 2020 Jun 2. PMID 32434916, Free PMC Article
    2. Drosophila cells use nanotube-like structures to transfer dsRNA and RNAi machinery between cells. Karlikow M, et al. Sci Rep, 2016 Jun 3. PMID 27255932, Free PMC Article
    3. Cp1/cathepsin L is required for autolysosomal clearance in Drosophila. Xu T, et al. Autophagy, 2021 Oct. PMID 33112206, Free PMC Article
    4. Antiviral immunity in Drosophila requires systemic RNA interference spread. Saleh MC, et al. Nature, 2009 Mar 19. PMID 19204732, Free PMC Article
    5. Neuronal expression in Drosophila of an evolutionarily conserved metallophosphodiesterase reveals pleiotropic roles in longevity and odorant response. Gupta K, et al. PLoS Genet, 2023 Sep. PMID 37733787, Free PMC Article

    See all (37) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables serine hydrolase activity HDA PubMed 
    enables serine-type carboxypeptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables serine-type carboxypeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG4572-PA
    CG4572-PB
    CG4572-PD
    NP_650836.1
    NP_732456.1
    NP_732457.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      19862517..19864393 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_169879.3 → NP_732457.1  uncharacterized protein Dmel_CG4572, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_732457.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VDT5
      Related
      FBpp0291533
      Conserved Domains (1) summary
      cl08270
      Location:83 → 479
      Peptidase_S10; Serine carboxypeptidase

    2. NM_169878.3 → NP_732456.1  uncharacterized protein Dmel_CG4572, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_732456.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VDT5
      Related
      FBpp0083269
      Conserved Domains (1) summary
      cl08270
      Location:83 → 479
      Peptidase_S10; Serine carboxypeptidase

    3. NM_142579.4 → NP_650836.1  uncharacterized protein Dmel_CG4572, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650836.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VDT5
      Related
      FBpp0083270
      Conserved Domains (1) summary
      cl08270
      Location:83 → 479
      Peptidase_S10; Serine carboxypeptidase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VDT5 Q9VDT5

    Gene LinkOut

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