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    Dtg Dpp target gene [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41558, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Dtgprovided by FlyBase
    Official Full Name
    Dpp target geneprovided by FlyBase
    Primary source
    FLYBASE:FBgn0038071
    Locus tag
    Dmel_CG6234
    See related
    AllianceGenome:FB:FBgn0038071
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG6234; Dmel\CG6234
    Summary
    Involved in gastrulation. Located in cell surface and vesicle. Is expressed in amnioserosa anlage; dorsal ectoderm; and presumptive wing vein. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Dtg in Genome Data Viewer
    Location:
    87C3-87C3; 3-52 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (12648058..12652910)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (8473780..8478632)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR46351 Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR45586

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The oligomeric state of CtBP determines its role as a transcriptional co-activator and co-repressor of Wingless targets. Bhambhani C, et al. EMBO J, 2011 May 18. PMID 21468031, Free PMC Article
    2. SMAD dependent signaling plays a detrimental role in a fly model of SMARCB1-deficiency and the biology of atypical teratoid/rhabdoid tumors. Jeibmann A, et al. J Neurooncol, 2017 Feb. PMID 28108836
    3. Novel TCF-binding sites specify transcriptional repression by Wnt signalling. Blauwkamp TA, et al. EMBO J, 2008 May 21. PMID 18418383, Free PMC Article
    4. C-terminal-binding protein directly activates and represses Wnt transcriptional targets in Drosophila. Fang M, et al. EMBO J, 2006 Jun 21. PMID 16710294, Free PMC Article
    5. Wnt/Frizzled signaling requires dPRR, the Drosophila homolog of the prorenin receptor. Buechling T, et al. Curr Biol, 2010 Jul 27. PMID 20579883

    See all (52) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in gastrulation IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cell surface IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in vesicle IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Dpp target gene
    Names
    CG6234-PA
    Dtg-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      12648058..12652910
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_141963.3 → NP_650220.2  Dpp target gene [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650220.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q960I9, Q9VG45
      Related
      FBpp0082117
      Conserved Domains (3) summary
      PTZ00341
      Location:112 → 325
      PTZ00341; Ring-infected erythrocyte surface antigen; Provisional
      PRK10811
      Location:303 → 445
      rne; ribonuclease E; Reviewed
      pfam11702
      Location:410 → 498
      DUF3295; Protein of unknown function (DUF3295)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q960I9 Q960I9
    Q9VG45 Q9VG45

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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