D12 D12 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: D12provided by FlyBase
Official Full Name: D12provided by FlyBase
Primary source: FLYBASE:FBgn0027490
Locus tag: Dmel_CG13400
See related: AllianceGenome:FB:FBgn0027490
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG13400; Dmel\CG13400; dYeats2; Yeats2
Summary: Predicted to enable histone binding activity. Involved in chromatin remodeling. Located in polytene chromosome. Part of ATAC complex. Is expressed in organism. Used to study familial adult myoclonic epilepsy 4. Human ortholog(s) of this gene implicated in familial adult myoclonic epilepsy 4. Orthologous to human YEATS2 (YEATS domain containing 2). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	2L	NT_033779.5 (8434058..8437365, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	2L	NT_033779.4 (8434058..8437365, complement)

Chromosome 2L - NT_033779.5 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

FAME4-associating YEATS2 knockdown impairs dopaminergic synaptic integrity and leads to seizure-like behaviours in Drosophila melanogaster.
Title: FAME4-associating YEATS2 knockdown impairs dopaminergic synaptic integrity and leads to seizure-like behaviours in Drosophila melanogaster.

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables histone binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in chromatin remodeling	IBA Inferred from Biological aspect of Ancestor more info
involved_in chromatin remodeling	IDA Inferred from Direct Assay more info	PubMed
involved_in regulation of DNA-templated transcription	IEA Inferred from Electronic Annotation more info
involved_in regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
part_of ATAC complex	IBA Inferred from Biological aspect of Ancestor more info
part_of ATAC complex	IDA Inferred from Direct Assay more info	PubMed
part_of ATAC complex	IPI Inferred from Physical Interaction more info	PubMed
part_of NuA4 histone acetyltransferase complex	IBA Inferred from Biological aspect of Ancestor more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in polytene chromosome	IDA Inferred from Direct Assay more info	PubMed