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    CG10996 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 32345, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG10996provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0030525
    Locus tag
    Dmel_CG10996
    See related
    AllianceGenome:FB:FBgn0030525
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG10996
    Summary
    Predicted to enable aldose 1-epimerase activity. Predicted to be involved in galactose catabolic process via UDP-galactose and glucose metabolic process. Predicted to be located in cytosol. Is expressed in spermatozoon. Human ortholog(s) of this gene implicated in galactosemia 4. Orthologous to human GALM (galactose mutarotase). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG10996 in Genome Data Viewer
    Location:
    12C5-12C5; 1-46 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (13796389..13797638, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (13690422..13691671, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene amaretto Neighboring gene inactivation no afterpotential E Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Chloride intracellular channel

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Evidence for the fixation of gene duplications by positive selection in Drosophila. Cardoso-Moreira M, et al. Genome Res, 2016 Jun. PMID 27197209, Free PMC Article
    2. Different modes of APC/C activation control growth and neuron-glia interaction in the developing Drosophila eye. Neuert H, et al. Development, 2017 Dec 15. PMID 29084807
    3. Proteome-wide dataset supporting the study of ancient metazoan macromolecular complexes. Phanse S, et al. Data Brief, 2016 Mar. PMID 26870755, Free PMC Article
    4. Phylostratigraphic bias creates spurious patterns of genome evolution. Moyers BA, et al. Mol Biol Evol, 2015 Jan. PMID 25312911, Free PMC Article
    5. A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function. Neely GG, et al. Cell, 2010 Apr 2. PMID 20371351, Free PMC Article

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables aldose 1-epimerase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables carbohydrate binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables isomerase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in carbohydrate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in galactose catabolic process via UDP-galactose IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in glucose metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in cytosol ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG10996-PA
    NP_572924.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      13796389..13797638 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_132696.2 → NP_572924.1  uncharacterized protein Dmel_CG10996 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_572924.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q29QR0, Q9VY83
      Related
      FBpp0073667
      Conserved Domains (1) summary
      cd09019
      Location:25 → 363
      galactose_mutarotase_like; galactose mutarotase_like
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VY83 Q9VY83

    Gene LinkOut

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