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    CG15373 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 32784, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG15373provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0030889
    Locus tag
    Dmel_CG15373
    See related
    AllianceGenome:FB:FBgn0030889
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG15373
    Summary
    Predicted to enable beta-tubulin binding activity and microtubule binding activity. Is expressed in spermatogonium. Orthologous to human DNAI7 (dynein axonemal intermediate chain 7). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG15373 in Genome Data Viewer
    Location:
    16F5-16F5; 1-59 cM
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (18043991..18048720)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (17938104..17942753)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene Shaker Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Dynein heavy chain at 16F Neighboring gene uncharacterized protein Neighboring gene transcriptional Adaptor 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Survey of the Ciliary Motility Machinery of Drosophila Sperm and Ciliated Mechanosensory Neurons Reveals Unexpected Cell-Type Specific Variations: A Model for Motile Ciliopathies. Zur Lage P, et al. Front Genet, 2019. PMID 30774648, Free PMC Article
    2. A comparative genomic analysis of two distant diptera, the fruit fly, Drosophila melanogaster, and the malaria mosquito, Anopheles gambiae. Bolshakov VN, et al. Genome Res, 2002 Jan. PMID 11779831, Free PMC Article
    3. A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function. Neely GG, et al. Cell, 2010 Apr 2. PMID 20371351, Free PMC Article
    4. A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene. Neely GG, et al. Cell, 2010 Nov 12. PMID 21074052, Free PMC Article
    5. Systematic genetic analysis of muscle morphogenesis and function in Drosophila. Schnorrer F, et al. Nature, 2010 Mar 11. PMID 20220848

    See all (18) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables beta-tubulin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables microtubule binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG15373-PD
    CG15373-PE

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      18043991..18048720
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001103543.3 → NP_001097013.2  uncharacterized protein Dmel_CG15373, isoform E [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8JUM9
      Conserved Domains (2) summary
      pfam12366
      Location:908 → 1118
      Casc1; Cancer susceptibility candidate 1
      pfam15927
      Location:14 → 267
      Casc1_N; Cancer susceptibility candidate 1 N-terminus

    2. NM_133036.3 → NP_573264.2  uncharacterized protein Dmel_CG15373, isoform D [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VWZ4
      Conserved Domains (2) summary
      pfam12366
      Location:879 → 1089
      Casc1; Cancer susceptibility candidate 1
      pfam15927
      Location:14 → 234
      Casc1_N; Cancer susceptibility candidate 1 N-terminus
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A8JUM9 A8JUM9
    Q9VWZ4 Q9VWZ4

    Gene LinkOut

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