U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    CG4382 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34279, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    CG4382provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0032132
    Locus tag
    Dmel_CG4382
    See related
    AllianceGenome:FB:FBgn0032132
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG4382
    Summary
    Is expressed in wing disc. Human ortholog(s) of this gene implicated in colorectal cancer and gastrointestinal system cancer. Orthologous to several human genes including CES1 (carboxylesterase 1); CES2 (carboxylesterase 2); and CES3 (carboxylesterase 3). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See CG4382 in Genome Data Viewer
    Location:
    30C1-30C1; 2-36 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (9598880..9600872, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (9598880..9600872, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR43621 Neighboring gene uncharacterized protein Neighboring gene gcm2 Neighboring gene Thioredoxin 2

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Transcriptional control of glial and blood cell development in Drosophila: cis-regulatory elements of glial cells missing. Jones BW, et al. Dev Biol, 2004 Feb 15. PMID 14738884
    2. Glide2, a second glial promoting factor in Drosophila melanogaster. Kammerer M, et al. EMBO J, 2001 Sep 3. PMID 11532931, Free PMC Article
    3. gcm2 promotes glial cell differentiation and is required with glial cells missing for macrophage development in Drosophila. Alfonso TB, et al. Dev Biol, 2002 Aug 15. PMID 12167411
    4. Studies on the glutathione S-transferase proteome of adult Drosophila melanogaster: responsiveness to chemical challenge. Alias Z, et al. Proteomics, 2007 Oct. PMID 17907271
    5. New negative feedback regulators of Egfr signaling in Drosophila. Butchar JP, et al. Genetics, 2012 Aug. PMID 22595244, Free PMC Article

    See all (29) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    NOT enables peptidase activity IKR
    Inferred from Key Residues
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    uncharacterized protein
    Names
    CG4382-PB

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      9598880..9600872 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_135457.3 → NP_609301.2  uncharacterized protein Dmel_CG4382 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609301.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      D6W4W1, Q9VLA3
      Conserved Domains (1) summary
      pfam00135
      Location:41 → 565
      COesterase; Carboxylesterase family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VLA3 Q9VLA3

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous