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    Obp59a Odorant-binding protein 59a [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37605, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Obp59aprovided by FlyBase
    Official Full Name
    Odorant-binding protein 59aprovided by FlyBase
    Primary source
    FLYBASE:FBgn0034766
    Locus tag
    Dmel_CG13517
    See related
    AllianceGenome:FB:FBgn0034766
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    59a; CG13517; DmelObp59a; Dmel\CG13517; Obp58a; OBP59a
    Summary
    Predicted to enable odorant binding activity. Involved in response to low humidity. Predicted to be located in extracellular region. Is expressed in antennal segment 3 sense organ and hygrosensitive sensory organ. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Obp59a in Genome Data Viewer
    Location:
    59A3-59A3; 2-101 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (22702695..22703786)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (18590200..18591291)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR44764 Neighboring gene roundabout 1 Neighboring gene uncharacterized protein Neighboring gene Odorant-binding protein 58b Neighboring gene Odorant-binding protein 58c

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Humidity response depends on the small soluble protein Obp59a in Drosophila. Sun JS, et al. Elife, 2018 Sep 19. PMID 30230472, Free PMC Article
    2. Molecular mechanisms of olfactory detection in insects: beyond receptors. Schmidt HR, et al. Open Biol, 2020 Oct. PMID 33022193, Free PMC Article
    3. Modulation of feeding behavior by odorant-binding proteins in Drosophila melanogaster. Swarup S, et al. Chem Senses, 2014 Feb. PMID 24302688, Free PMC Article
    4. Functional dissection of Odorant binding protein genes in Drosophila melanogaster. Swarup S, et al. Genes Brain Behav, 2011 Aug. PMID 21605338, Free PMC Article
    5. Organization and function of Drosophila odorant binding proteins. Larter NK, et al. Elife, 2016 Nov 15. PMID 27845621, Free PMC Article

    See all (41) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables odorant binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables odorant binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in response to low humidity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in sensory perception of chemical stimulus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Odorant-binding protein 59a
    Names
    CG13517-PB
    Obp59a-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      22702695..22703786
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_176249.3 → NP_788429.1  Odorant-binding protein 59a [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_788429.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q29QE9, Q86BF9
      Related
      FBpp0071781
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q86BF9.1 Q86BF9

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