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    Srp9 Signal recognition particle 9 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38883, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Srp9provided by FlyBase
    Official Full Name
    Signal recognition particle 9provided by FlyBase
    Primary source
    FLYBASE:FBgn0035827
    Locus tag
    Dmel_CG8268
    See related
    AllianceGenome:FB:FBgn0035827
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG8268; Dmel\CG8268; SRP9
    Summary
    Predicted to enable 7S RNA binding activity. Predicted to be involved in SRP-dependent cotranslational protein targeting to membrane. Predicted to be part of signal recognition particle, endoplasmic reticulum targeting. Is expressed in adult head; embryonic/larval salivary gland; embryonic/larval salivary gland body; organism; and salivary gland body primordium. Orthologous to human SRP9 (signal recognition particle 9). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Srp9 in Genome Data Viewer
    Location:
    66A20-66A20; 3-21 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (7936373..7937258)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (7929473..7930358)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR32368 Neighboring gene sunday driver Neighboring gene uncharacterized protein Neighboring gene extra-extra

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Nascent polypeptide-Associated Complex and Signal Recognition Particle have cardiac-specific roles in heart development and remodeling. Schroeder AM, et al. PLoS Genet, 2022 Oct. PMID 36240221, Free PMC Article
    2. The CrebA/Creb3-like transcription factors are major and direct regulators of secretory capacity. Fox RM, et al. J Cell Biol, 2010 Nov 1. PMID 21041443, Free PMC Article
    3. CrebA regulates secretory activity in the Drosophila salivary gland and epidermis. Abrams EW, et al. Development, 2005 Jun. PMID 15901661
    4. Genome-wide P-element screen for Drosophila synaptogenesis mutants. Liebl FL, et al. J Neurobiol, 2006 Mar. PMID 16408305, Free PMC Article
    5. C9orf72 Dipeptide Repeats Impair the Assembly, Dynamics, and Function of Membrane-Less Organelles. Lee KH, et al. Cell, 2016 Oct 20. PMID 27768896, Free PMC Article

    See all (32) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables 7S RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in SRP-dependent cotranslational protein targeting to membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in SRP-dependent cotranslational protein targeting to membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in negative regulation of translational elongation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of signal recognition particle IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of signal recognition particle, endoplasmic reticulum targeting IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    signal recognition particle 9
    Names
    CG8268-PA
    Srp9-PA
    signal recognition particle protein 9

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      7936373..7937258
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_139906.3 → NP_648163.1  signal recognition particle 9 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648163.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VSC1
      Related
      FBpp0076467
      Conserved Domains (1) summary
      pfam05486
      Location:4 → 73
      SRP9-21; Signal recognition particle 9 kDa protein (SRP9)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VSC1.1 Q9VSC1

    Gene LinkOut

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