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    Ir75b Ionotropic receptor 75b [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 8673994, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Ir75bprovided by FlyBase
    Official Full Name
    Ionotropic receptor 75bprovided by FlyBase
    Primary source
    FLYBASE:FBgn0261402
    Locus tag
    Dmel_CG42643
    See related
    AllianceGenome:FB:FBgn0261402
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    75b; CG14586; CG14586-B; CG42643; DmelIR75b; Dmel\CG42643; Ir75abc; IR75abc; IR75b
    Summary
    Predicted to enable ligand-gated monoatomic ion channel activity. Involved in detection of chemical stimulus involved in sensory perception. Predicted to be located in membrane. Is expressed in antennal coeloconic sensillum ac3. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Ir75b in Genome Data Viewer
    Location:
    75A2-75A2; 3-45 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (17818073..17820193, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (17811173..17813293, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Cln3 Neighboring gene Ionotropic receptor 75a Neighboring gene Ionotropic receptor 75c Neighboring gene Glycine receptor Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Odor-regulated oviposition behavior in an ecological specialist. Álvarez-Ocaña R, et al. Nat Commun, 2023 May 26. PMID 37236992, Free PMC Article
    2. Molecular reconstruction of recurrent evolutionary switching in olfactory receptor specificity. Prieto-Godino LL, et al. Elife, 2021 Oct 22. PMID 34677122, Free PMC Article
    3. Evolution of Acid-Sensing Olfactory Circuits in Drosophilids. Prieto-Godino LL, et al. Neuron, 2017 Feb 8. PMID 28111079
    4. Olfactory receptor pseudo-pseudogenes. Prieto-Godino LL, et al. Nature, 2016 Nov 3. PMID 27776356, Free PMC Article
    5. Olfactory receptor-dependent receptor repression in Drosophila. Mika K, et al. Sci Adv, 2021 Aug. PMID 34362730, Free PMC Article

    See all (44) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ligand-gated monoatomic ion channel activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ligand-gated monoatomic ion channel activity ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in detection of chemical stimulus involved in sensory perception IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ionotropic receptor 75b
    Names
    CG42643-PA
    Ir75b-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      17818073..17820193 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001144494.2 → NP_001137966.2  ionotropic receptor 75b [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001137966.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1S6EMU4, B7Z069
      Conserved Domains (2) summary
      pfam00060
      Location:343 → 585
      Lig_chan; Ligand-gated ion channel
      cl21456
      Location:253 → 553
      Periplasmic_Binding_Protein_Type_2; Type 2 periplasmic binding fold superfamily
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    B7Z069 B7Z069

    Gene LinkOut

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