CG16779 uncharacterized protein [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: CG16779provided by FlyBase
Official Full Name: uncharacterized proteinprovided by FlyBase
Primary source: FLYBASE:FBgn0037698
Locus tag: Dmel_CG16779
See related: AllianceGenome:FB:FBgn0037698
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: Dmel\CG16779
Summary: Predicted to enable transcription corepressor activity. Predicted to be involved in negative regulation of DNA-templated transcription and regulation of transcription by RNA polymerase II. Predicted to be part of histone deacetylase complex and transcription regulator complex. Orthologous to human MIDEAS (mitotic deacetylase associated SANT domain protein); TRERF1 (transcriptional regulating factor 1); and ZNF541 (zinc finger protein 541). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: 85D17-85D18; 3-48 cM

Exon count:: 13

Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3R	NT_033777.3 (9461084..9493677, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3R	NT_033777.2 (5286806..5319399, complement)

Chromosome 3R - NT_033777.3 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by FlyBase

Function	Evidence Code	Pubs
enables transcription corepressor activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in negative regulation of DNA-templated transcription	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
part_of histone deacetylase complex	IBA Inferred from Biological aspect of Ancestor more info
part_of transcription regulator complex	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: uncharacterized protein

Names: CG16779-PB; CG16779-PC; CG16779-PD; CG16779-PF; CG16779-PG

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NT_033777.3 Reference assembly

Range

9461084..9493677 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001275489.2 → NP_001262418.1 uncharacterized protein Dmel_CG16779, isoform D [Drosophila melanogaster]

See identical proteins and their annotated locations for NP_001262418.1

Status: REVIEWED

UniProtKB/TrEMBL

A0A0B4KFG7

Conserved Domains (6) summary

smart00717
Location:1713 → 1757

SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains

COG5048
Location:319 → 383

COG5048; FOG: Zn-finger [General function prediction only]

sd00017
Location:304 → 324

ZF_C2H2; C2H2 Zn finger [structural motif]

pfam00096
Location:330 → 352

zf-C2H2; Zinc finger, C2H2 type

pfam01448
Location:1622 → 1671

ELM2; ELM2 domain

cl21498
Location:1713 → 1757

SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
NM_001275487.2 → NP_001262416.1 uncharacterized protein Dmel_CG16779, isoform B [Drosophila melanogaster]

See identical proteins and their annotated locations for NP_001262416.1

Status: REVIEWED

UniProtKB/TrEMBL

A0A0B4KGL1

Conserved Domains (6) summary

smart00717
Location:1713 → 1757

SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains

COG5048
Location:319 → 383

COG5048; FOG: Zn-finger [General function prediction only]

sd00017
Location:304 → 324

ZF_C2H2; C2H2 Zn finger [structural motif]

pfam00096
Location:330 → 352

zf-C2H2; Zinc finger, C2H2 type

pfam01448
Location:1622 → 1671

ELM2; ELM2 domain

cl21498
Location:1713 → 1757

SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
NM_001275488.2 → NP_001262417.1 uncharacterized protein Dmel_CG16779, isoform C [Drosophila melanogaster]

See identical proteins and their annotated locations for NP_001262417.1

Status: REVIEWED

UniProtKB/TrEMBL

A0A0B4KFL1

Conserved Domains (6) summary

smart00717
Location:1713 → 1757

SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains

COG5048
Location:319 → 383

COG5048; FOG: Zn-finger [General function prediction only]

sd00017
Location:304 → 324

ZF_C2H2; C2H2 Zn finger [structural motif]

pfam00096
Location:330 → 352

zf-C2H2; Zinc finger, C2H2 type

pfam01448
Location:1622 → 1671

ELM2; ELM2 domain

cl21498
Location:1713 → 1757

SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
NM_001300325.1 → NP_001287254.2 uncharacterized protein Dmel_CG16779, isoform G [Drosophila melanogaster]

Status: REVIEWED

UniProtKB/TrEMBL

Q9VHD1

Conserved Domains (5) summary

sd00017
Location:329 → 349

ZF_C2H2; C2H2 Zn finger [structural motif]

pfam00096
Location:355 → 377

zf-C2H2; Zinc finger, C2H2 type

pfam01448
Location:1647 → 1696

ELM2; ELM2 domain

pfam13912
Location:1952 → 1975

zf-C2H2_6; C2H2-type zinc finger

cl21498
Location:1738 → 1782

SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
NM_141639.3 → NP_649896.2 uncharacterized protein Dmel_CG16779, isoform F [Drosophila melanogaster]

Status: REVIEWED

UniProtKB/TrEMBL

Q9VHD1

Conserved Domains (5) summary

sd00017
Location:329 → 349

ZF_C2H2; C2H2 Zn finger [structural motif]

pfam00096
Location:355 → 377

zf-C2H2; Zinc finger, C2H2 type

pfam01448
Location:1647 → 1696

ELM2; ELM2 domain

pfam13912
Location:1952 → 1975

zf-C2H2_6; C2H2-type zinc finger

cl21498
Location:1738 → 1782

SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...