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    RpL27 Ribosomal protein L27 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43103, updated on 9-Dec-2024

    Summary

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    Official Symbol
    RpL27provided by FlyBase
    Official Full Name
    Ribosomal protein L27provided by FlyBase
    Primary source
    FLYBASE:FBgn0039359
    Locus tag
    Dmel_CG4759
    See related
    AllianceGenome:FB:FBgn0039359
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG4759; chr3R:21510055..21510241; Dmel\CG4759; L27e; RPL27; RpL27e
    Summary
    A structural constituent of ribosome. Predicted to be involved in cytoplasmic translation. Located in cytosolic ribosome. Is expressed in adult head; adult heart; and organism. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 16. Orthologous to human RPL27 (ribosomal protein L27). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See RpL27 in Genome Data Viewer
    Location:
    96E9-96E10; 3-88 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (25683623..25685051, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (21509345..21510773, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Leucine-rich repeat-containing G protein-coupled receptor 3 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma Neighboring gene Cardiolipin synthase Neighboring gene Lipophorin receptor 2 Neighboring gene long non-coding RNA:CR46102

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Ribosomal protein mutations and cell competition: autonomous and nonautonomous effects on a stress response. Kiparaki M, et al. Genetics, 2023 Jul 6. PMID 37267156, Free PMC Article
    2. New partners in regulation of gene expression: the enhancer of Trithorax and Polycomb Corto interacts with methylated ribosomal protein l12 via its chromodomain. Coléno-Costes A, et al. PLoS Genet, 2012. PMID 23071455, Free PMC Article
    3. Small ribonucleoprotein particle protein SmD3 governs the homeostasis of germline stem cells and the crosstalk between the spliceosome and ribosome signals in Drosophila. Yu J, et al. FASEB J, 2019 Jul. PMID 30921522
    4. DREF is required for cell and organismal growth in Drosophila and functions downstream of the nutrition/TOR pathway. Killip LE, et al. Dev Biol, 2012 Nov 15. PMID 22960233
    5. RpS13 controls the homeostasis of germline stem cell niche through Rho1-mediated signals in the Drosophila testis. Wang M, et al. Cell Prolif, 2020 Oct. PMID 32896929, Free PMC Article

    See all (60) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables structural constituent of ribosome TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cytoplasmic translation IC
    Inferred by Curator
    more info
    		 PubMed 
    involved_in cytoplasmic translation TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of cytosolic large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of cytosolic large ribosomal subunit TAS
    Traceable Author Statement
    more info
    		 PubMed 
    located_in cytosolic ribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ribosomal protein L27
    Names
    CG4759-PA
    CG4759-PB
    CG4759-PC
    CG4759-PD
    RpL27-PA
    RpL27-PB
    RpL27-PC
    RpL27-PD

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      25683623..25685051 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001276039.1 → NP_001262968.1  ribosomal protein L27, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262968.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VBN5
      Conserved Domains (1) summary
      cl00354
      Location:1 → 135
      KOW; an acronym for the authors' surnames (Kyrpides, Ouzounis and Woese)

    2. NM_143160.2 → NP_651417.1  ribosomal protein L27, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651417.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VBN5
      Related
      FBpp0084306
      Conserved Domains (1) summary
      cl00354
      Location:1 → 135
      KOW; an acronym for the authors' surnames (Kyrpides, Ouzounis and Woese)

    3. NM_001276038.1 → NP_001262967.1  ribosomal protein L27, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262967.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VBN5
      Conserved Domains (1) summary
      cl00354
      Location:1 → 135
      KOW; an acronym for the authors' surnames (Kyrpides, Ouzounis and Woese)

    4. NM_001276037.1 → NP_001262966.1  ribosomal protein L27, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262966.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VBN5
      Conserved Domains (1) summary
      cl00354
      Location:1 → 135
      KOW; an acronym for the authors' surnames (Kyrpides, Ouzounis and Woese)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VBN5 Q9VBN5

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