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    CG15531 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43592, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG15531provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0039755
    Locus tag
    Dmel_CG15531
    See related
    AllianceGenome:FB:FBgn0039755
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG15531
    Summary
    Predicted to enable iron ion binding activity and stearoyl-CoA 9-desaturase activity. Predicted to be involved in unsaturated fatty acid biosynthetic process. Predicted to be active in endoplasmic reticulum membrane. Is expressed in adult head and adult heart. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 79. Orthologous to human SCD (stearoyl-CoA desaturase) and SCD5 (stearoyl-CoA desaturase 5). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG15531 in Genome Data Viewer
    Location:
    99E2-99E2; 3-100 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (30194790..30196228, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (26020512..26021950, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR44262 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene Ribosomal protein S7

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Molecular genetics and evolution of pheromone biosynthesis in Lepidoptera. Roelofs WL, et al. Proc Natl Acad Sci U S A, 2003 Aug 5. PMID 12876197, Free PMC Article
    2. Widespread polymorphism in the positions of stop codons in Drosophila melanogaster. Lee YC, et al. Genome Biol Evol, 2012. PMID 22051795, Free PMC Article
    3. Seasonal gene expression kinetics between diapause phases in Drosophila virilis group species and overwintering differences between diapausing and non-diapausing females. Salminen TS, et al. Sci Rep, 2015 Jun 11. PMID 26063442, Free PMC Article
    4. Mosaic genetic screen for suppressors of the de2f1 mutant phenotype in Drosophila. Ambrus AM, et al. Genetics, 2009 Sep. PMID 19546319, Free PMC Article
    5. Molecular evolution and functional diversification of fatty acid desaturases after recurrent gene duplication in Drosophila. Fang S, et al. Mol Biol Evol, 2009 Jul. PMID 19307313, Free PMC Article

    See all (38) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables iron ion binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables stearoyl-CoA 9-desaturase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables stearoyl-CoA 9-desaturase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in unsaturated fatty acid biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG15531-PA
    NP_651780.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      30194790..30196228 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_143523.3 → NP_651780.1  uncharacterized protein Dmel_CG15531 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651780.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q4V4B1, Q9VA93
      Related
      FBpp0084938
      Conserved Domains (1) summary
      cd03505
      Location:49 → 286
      Delta9-FADS-like; The Delta9 Fatty Acid Desaturase (Delta9-FADS)-like CD includes the delta-9 and delta-11 acyl CoA desaturases found in various eukaryotes including vertebrates, insects, higher plants, and fungi. The delta-9 acyl-lipid desaturases are found in a wide ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VA93 Q9VA93

    Gene LinkOut

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