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    CG13018 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 50224, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG13018provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0040751
    Locus tag
    Dmel_CG13018
    See related
    AllianceGenome:FB:FBgn0040751
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG13018
    Summary
    Predicted to be involved in mitochondrial cytochrome c oxidase assembly. Predicted to be active in mitochondrion. Is expressed in embryonic/larval midgut. Human ortholog(s) of this gene implicated in mitochondrial complex IV deficiency nuclear type 9. Orthologous to human COA5 (cytochrome c oxidase assembly factor 5). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG13018 in Genome Data Viewer
    Location:
    50E1-50E1; 2-69 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (14157050..14157488, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (10044555..10044993, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene mir-989 stem loop Neighboring gene Reduction in Cnn dots 1 Neighboring gene peanuts Neighboring gene uncharacterized protein Neighboring gene Cysteinyl-tRNA synthetase, mitochondrial Neighboring gene O-fucosyltransferase 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Developmental regulation of canonical and small ORF translation from mRNAs. Patraquim P, et al. Genome Biol, 2020 May 29. PMID 32471506, Free PMC Article
    2. The pleiotropic functions of Pri smORF peptides synchronize leg development regulators. Markus D, et al. PLoS Genet, 2023 Oct. PMID 37903161, Free PMC Article
    3. Cell competition removes segmental aneuploid cells from Drosophila imaginal disc-derived tissues based on ribosomal protein gene dose. Ji Z, et al. Elife, 2021 Apr 13. PMID 33847264, Free PMC Article
    4. Ultra-deep sequencing of ribosome-associated poly-adenylated RNA in early Drosophila embryos reveals hundreds of conserved translated sORFs. Li H, et al. DNA Res, 2016 Dec. PMID 27559081, Free PMC Article
    5. mRNA-Associated Processes and Their Influence on Exon-Intron Structure in Drosophila melanogaster. Lepennetier G, et al. G3 (Bethesda), 2016 Jun 1. PMID 27172210, Free PMC Article

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in mitochondrial cytochrome c oxidase assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mitochondrial cytochrome c oxidase assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrion ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG13018-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      14157050..14157488 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_144123.3 → NP_652380.2  uncharacterized protein Dmel_CG13018 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_652380.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q4V429
      Related
      FBpp0086707
      Conserved Domains (1) summary
      pfam10203
      Location:15 → 76
      Pet191_N; Cytochrome c oxidase assembly protein PET191
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q4V429 Q4V429

    Gene LinkOut

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