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    mri mrityu [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38028, updated on 9-Dec-2024

    Summary

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    Official Symbol
    mriprovided by FlyBase
    Official Full Name
    mrityuprovided by FlyBase
    Primary source
    FLYBASE:FBgn0035107
    Locus tag
    Dmel_CG1216
    See related
    AllianceGenome:FB:FBgn0035107
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG1216; Dmel\CG1216; Mri
    Summary
    Involved in sensory perception of touch. Predicted to be active in cytoplasm. Is expressed in several structures, including anterior-posterior subdivision of organism; embryonic/larval gut; germline cell; imaginal disc; and sensory organ cell. Orthologous to human BTBD10 (BTB domain containing 10) and KCTD20 (potassium channel tetramerization domain containing 20). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See mri in Genome Data Viewer
    Location:
    61B2-61B2; 3-1 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (200174..202152)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (200174..202152)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Mitochondrial carrier homolog 1 Neighboring gene rhinoceros Neighboring gene Glycerol kinase 1 Neighboring gene Nitrilase and fragile histidine triad fusion protein Neighboring gene uncharacterized protein Neighboring gene Pre-mRNA processing factor 4 kinase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Drosophila Mrityu encodes a BTB/POZ domain-containing protein and is expressed dynamically during development. Rusconi JC, et al. Int J Dev Biol, 2007. PMID 17486548
    2. Conserved family of glycerol kinase loci in Drosophila melanogaster. Martinez Agosto JA, et al. Mol Genet Metab, 2006 Aug. PMID 16545593, Free PMC Article
    3. Analysing bioelectrical phenomena in the Drosophila ovary with genetic tools: tissue-specific expression of sensors for membrane potential and intracellular pH, and RNAi-knockdown of mechanisms involved in ion exchange. Schotthöfer SK, et al. BMC Dev Biol, 2020 Jul 8. PMID 32635900, Free PMC Article
    4. Dendritic filopodia, Ripped Pocket, NOMPC, and NMDARs contribute to the sense of touch in Drosophila larvae. Tsubouchi A, et al. Curr Biol, 2012 Nov 20. PMID 23103192, Free PMC Article
    5. The GAGA factor regulatory network: Identification of GAGA factor associated proteins. Lomaev D, et al. PLoS One, 2017. PMID 28296955, Free PMC Article

    See all (43) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. mrityu encodes a BTB/POZ domain-containing protein and is expressed dynamically during development.
      Title: Drosophila Mrityu encodes a BTB/POZ domain-containing protein and is expressed dynamically during development.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    NOT enables glycerol kinase activity IKR
    Inferred from Key Residues
    more info
    		 PubMed 
    NOT enables transferase activity IKR
    Inferred from Key Residues
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in sensory perception of touch IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    mrityu
    Names
    CG1216-PA
    CG1216-PB
    CG1216-PE
    mri-PA
    mri-PB
    mri-PE

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      200174..202152
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_167801.3 → NP_728484.1  mrityu, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_728484.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0E8K5
      Related
      FBpp0072383
      Conserved Domains (2) summary
      smart00225
      Location:98 → 199
      BTB; Broad-Complex, Tramtrack and Bric a brac
      pfam16017
      Location:128 → 357
      BTB_3; BTB/POZ domain

    2. NM_001299954.1 → NP_001286883.1  mrityu, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286883.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      X2J8G3
      Conserved Domains (2) summary
      smart00225
      Location:98 → 199
      BTB; Broad-Complex, Tramtrack and Bric a brac
      pfam16017
      Location:128 → 356
      BTB_3; BTB/POZ domain

    3. NM_138164.4 → NP_612008.1  mrityu, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_612008.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0E8K5
      Related
      FBpp0072382
      Conserved Domains (2) summary
      smart00225
      Location:98 → 199
      BTB; Broad-Complex, Tramtrack and Bric a brac
      pfam16017
      Location:128 → 357
      BTB_3; BTB/POZ domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q0E8K5 Q0E8K5
    Q8SXB5 Q8SXB5
    X2J8G3 X2J8G3

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