eIF3m eukaryotic translation initiation factor 3 subunit m [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: eIF3mprovided by FlyBase
Official Full Name: eukaryotic translation initiation factor 3 subunit mprovided by FlyBase
Primary source: FLYBASE:FBgn0033902
Locus tag: Dmel_CG8309
See related: AllianceGenome:FB:FBgn0033902
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: anon-EST:Posey67; anon-EST:Posey76; CG8309; Dmel\CG8309; eIF3M; Tango 7; tango7; Tango7; TANGO7; Tng7
Summary: Enables caspase binding activity and cysteine-type endopeptidase activator activity. Involved in Golgi organization; protein secretion; and sperm individualization. Located in Golgi apparatus; cytosol; and investment cone. Is expressed in adult head; embryonic hindgut; embryonic/larval midgut; and organism. Orthologous to human EIF3M (eukaryotic translation initiation factor 3 subunit M). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	2R	NT_033778.4 (14163066..14164825, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	2R	NT_033778.3 (10050571..10052330, complement)

Chromosome 2R - NT_033778.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables caspase binding	IPI Inferred from Physical Interaction more info	PubMed
enables cysteine-type endopeptidase activator activity	IDA Inferred from Direct Assay more info	PubMed
enables translation initiation factor activity	IEA Inferred from Electronic Annotation more info
enables translation initiation factor binding	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
involved_in Golgi organization	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in cytoplasmic translational initiation	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein secretion	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in sperm individualization	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in translation	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in Golgi apparatus	IDA Inferred from Direct Assay more info	PubMed
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytosol	IDA Inferred from Direct Assay more info	PubMed
part_of eukaryotic translation initiation factor 3 complex	IBA Inferred from Biological aspect of Ancestor more info
part_of eukaryotic translation initiation factor 3 complex	IEA Inferred from Electronic Annotation more info
part_of eukaryotic translation initiation factor 3 complex	ISS Inferred from Sequence or Structural Similarity more info
located_in investment cone	IDA Inferred from Direct Assay more info	PubMed

Names: CG8309-PA; CG8309-PB; eIF3m-PA; eIF3m-PB; transport and golgi organization 7

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The following sections contain reference sequences that belong to a specific genome build. Explain