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    CG9135 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33850, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG9135provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0031769
    Locus tag
    Dmel_CG9135
    See related
    AllianceGenome:FB:FBgn0031769
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG9135
    Summary
    Predicted to enable small GTPase binding activity. Predicted to be involved in chromosome passenger complex localization to kinetochore and positive regulation of attachment of spindle microtubules to kinetochore. Predicted to be active in membrane. Is expressed in several structures, including antennal primordium; anterior endoderm anlage; ganglia; head epidermis primordium; and sensory nervous system primordium. Orthologous to human RCC2 (regulator of chromosome condensation 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG9135 in Genome Data Viewer
    Location:
    26B3-26B3; 2-18 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (6050800..6053877)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (6050800..6053877)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Phosphoribosylformylglycinamidine synthase Neighboring gene mir-966 stem loop Neighboring gene uncharacterized protein Neighboring gene slowmo Neighboring gene Inositol phosphatase interacting protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene NADH dehydrogenase (ubiquinone) 51 kDa subunit

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic variation in a member of the laminin gene family affects variation in body composition in Drosophila and humans. De Luca M, et al. BMC Genet, 2008 Aug 11. PMID 18694491, Free PMC Article
    2. Genome-wide DNA replication profile for Drosophila melanogaster: a link between transcription and replication timing. Schübeler D, et al. Nat Genet, 2002 Nov. PMID 12355067
    3. Variant histone H3.3 is deposited at sites of nucleosomal displacement throughout transcribed genes while active histone modifications show a promoter-proximal bias. Wirbelauer C, et al. Genes Dev, 2005 Aug 1. PMID 16077006, Free PMC Article
    4. Localized H3K36 methylation states define histone H4K16 acetylation during transcriptional elongation in Drosophila. Bell O, et al. EMBO J, 2007 Dec 12. PMID 18007591, Free PMC Article
    5. Functional screening of mammalian mechanosensitive genes using Drosophila RNAi library- Smarcd3/Bap60 is a mechanosensitive pro-inflammatory gene. Kumar S, et al. Sci Rep, 2016 Nov 7. PMID 27819340, Free PMC Article

    See all (37) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables small GTPase binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in chromosome passenger complex localization to kinetochore IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in positive regulation of attachment of spindle microtubules to kinetochore IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG9135-PA
    CG9135-PB
    CG9135-PC
    CG9135-PD

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      6050800..6053877
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001298727.1 → NP_001285656.1  uncharacterized protein Dmel_CG9135, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285656.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VMI5
      Conserved Domains (2) summary
      pfam00415
      Location:317 → 366
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam13540
      Location:171 → 200
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat

    2. NM_001298726.1 → NP_001285655.1  uncharacterized protein Dmel_CG9135, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285655.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VMI5
      Conserved Domains (2) summary
      pfam00415
      Location:317 → 366
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam13540
      Location:171 → 200
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat

    3. NM_164679.2 → NP_723150.1  uncharacterized protein Dmel_CG9135, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_723150.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VMI5
      Related
      FBpp0078817
      Conserved Domains (2) summary
      pfam00415
      Location:317 → 366
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam13540
      Location:171 → 200
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat

    4. NM_135141.3 → NP_608985.1  uncharacterized protein Dmel_CG9135, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_608985.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VMI5
      Related
      FBpp0078816
      Conserved Domains (2) summary
      pfam00415
      Location:317 → 366
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam13540
      Location:171 → 200
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VMI5 Q9VMI5

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