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    CG7744 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37239, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG7744provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0034447
    Locus tag
    Dmel_CG7744
    See related
    AllianceGenome:FB:FBgn0034447
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG7744
    Summary
    Predicted to enable actin filament binding activity and lamin binding activity. Predicted to be involved in nuclear migration along microtubule. Predicted to be active in nuclear membrane. Is expressed in adult brain and adult pars intercerebralis. Orthologous to human TMEM201 (transmembrane protein 201). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG7744 in Genome Data Viewer
    Location:
    56D8-56D9; 2-89 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (19452504..19455527)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (15340009..15343032)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene beta-Tubulin at 56D Neighboring gene Elongin C Neighboring gene meiotic W68 Neighboring gene par-1 Neighboring gene Tubulin-binding cofactor B

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Selection, recombination and demographic history in Drosophila miranda. Bachtrog D, et al. Genetics, 2006 Dec. PMID 17028331, Free PMC Article
    2. Inactivation of Hippo and cJun-N-terminal Kinase (JNK) signaling mitigate FUS mediated neurodegeneration in vivo. Gogia N, et al. Neurobiol Dis, 2020 Jul. PMID 32199908, Free PMC Article
    3. Functional variants identify sex-specific genes and pathways in Alzheimer's Disease. Bourquard T, et al. Nat Commun, 2023 May 13. PMID 37179358, Free PMC Article
    4. Drosophila functional screening of de novo variants in autism uncovers damaging variants and facilitates discovery of rare neurodevelopmental diseases. Marcogliese PC, et al. Cell Rep, 2022 Mar 15. PMID 35294868, Free PMC Article
    5. A gene-specific T2A-GAL4 library for Drosophila. Lee PT, et al. Elife, 2018 Mar 22. PMID 29565247, Free PMC Article

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables actin filament binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables lamin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in nuclear migration along microtubule IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nuclear membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG7744-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      19452504..19455527
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_137578.4 → NP_611422.2  uncharacterized protein Dmel_CG7744 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611422.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1ZBL2, B6IDT1, Q95R39
      Related
      FBpp0085719
      Conserved Domains (1) summary
      pfam09779
      Location:42 → 172
      Ima1_N; Ima1 N-terminal domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A1ZBL2 A1ZBL2
    Q95R39 Q95R39

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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