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    CHKov2 CHK domain ov2 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43068, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CHKov2provided by FlyBase
    Official Full Name
    CHK domain ov2provided by FlyBase
    Primary source
    FLYBASE:FBgn0039328
    Locus tag
    Dmel_CG10675
    See related
    AllianceGenome:FB:FBgn0039328
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG10675; Dmel\CG10675; Dro19-0; ref(3)D
    Summary
    Predicted to enable ecdysteroid 22-kinase activity. Is expressed in adult fat body; embryonic proventriculus; and embryonic/larval salivary gland. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CHKov2 in Genome Data Viewer
    Location:
    96D1-96D1; 3-87 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (25329530..25331203, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (21155252..21156925, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene CHK domain ov1 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Successive increases in the resistance of Drosophila to viral infection through a transposon insertion followed by a Duplication. Magwire MM, et al. PLoS Genet, 2011 Oct. PMID 22028673, Free PMC Article
    2. Pesticide resistance via transposition-mediated adaptive gene truncation in Drosophila. Aminetzach YT, et al. Science, 2005 Jul 29. PMID 16051794
    3. [Drosophila genes which intervene in multiplication of sigma virus (author's transl)]. Gay P. Mol Gen Genet, 1978 Feb 27. PMID 416336
    4. Population genomics of transposable elements in Drosophila. Barrón MG, et al. Annu Rev Genet, 2014. PMID 25292358
    5. Genomes from historical Drosophila melanogaster specimens illuminate adaptive and demographic changes across more than 200 years of evolution. Shpak M, et al. PLoS Biol, 2023 Oct. PMID 37824452, Free PMC Article

    See all (29) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ecdysteroid 22-kinase activity TAS
    Traceable Author Statement
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    CHK domain ov2
    Names
    CG10675-PA
    CHKov2-PA
    refractory to sigma D

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      25329530..25331203 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_143130.4 → NP_651387.1  CHK domain ov2 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651387.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95U10, Q9VBS0
      Related
      FBpp0084223
      Conserved Domains (1) summary
      pfam02958
      Location:40 → 326
      EcKinase; Ecdysteroid kinase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VBS0 Q9VBS0

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