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    CG17187 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41351, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG17187provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0037882
    Locus tag
    Dmel_CG17187
    See related
    AllianceGenome:FB:FBgn0037882
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:RE47242; Dmel\CG17187
    Summary
    Predicted to enable nucleic acid binding activity. Predicted to be involved in spliceosomal complex disassembly. Part of precatalytic spliceosome. Orthologous to human DNAJC17 (DnaJ heat shock protein family (Hsp40) member C17). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG17187 in Genome Data Viewer
    Location:
    86D8-86D8; 3-50 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (11230617..11231879, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (7056339..7057601, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene SCP-containing protein C Neighboring gene uncharacterized protein Neighboring gene GRIP and coiled-coil domain containing 88 kDa Neighboring gene Diphthamide biosynthesis 3 Neighboring gene Arfaptin Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A yeast functional screen predicts new candidate ALS disease genes. Couthouis J, et al. Proc Natl Acad Sci U S A, 2011 Dec 27. PMID 22065782, Free PMC Article
    2. RNAi-Mediated Reverse Genetic Screen Identified Drosophila Chaperones Regulating Eye and Neuromuscular Junction Morphology. Raut S, et al. G3 (Bethesda), 2017 Jul 5. PMID 28500055, Free PMC Article
    3. Mettl3-dependent m(6)A modification attenuates the brain stress response in Drosophila. Perlegos AE, et al. Nat Commun, 2022 Sep 14. PMID 36104353, Free PMC Article
    4. Conservation of the protein composition and electron microscopy structure of Drosophila melanogaster and human spliceosomal complexes. Herold N, et al. Mol Cell Biol, 2009 Jan. PMID 18981222, Free PMC Article
    5. spenito is required for sex determination in Drosophila melanogaster. Yan D, et al. Proc Natl Acad Sci U S A, 2015 Sep 15. PMID 26324914, Free PMC Article

    See all (29) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in mRNA splicing, via spliceosome IC
    Inferred by Curator
    more info
    		 PubMed 
    involved_in spliceosomal complex disassembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of precatalytic spliceosome HDA PubMed 
    part_of spliceosomal complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG17187-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      11230617..11231879 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_141799.2 → NP_650056.1  uncharacterized protein Dmel_CG17187 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650056.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VGR0
      Related
      FBpp0081841
      Conserved Domains (2) summary
      cd12429
      Location:175 → 247
      RRM_DNAJC17; RNA recognition motif in the DnaJ homolog subfamily C member 17
      pfam00226
      Location:10 → 72
      DnaJ; DnaJ domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VGR0 Q9VGR0

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
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