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    LysX Lysozyme X [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38122, updated on 9-Dec-2024

    Summary

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    Official Symbol
    LysXprovided by FlyBase
    Official Full Name
    Lysozyme Xprovided by FlyBase
    Primary source
    FLYBASE:FBgn0004431
    Locus tag
    Dmel_CG9120
    See related
    AllianceGenome:FB:FBgn0004431
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:LP09906; CG9120; Dmel\CG9120; lysX
    Summary
    Predicted to enable lysozyme activity. Predicted to be involved in defense response to Gram-negative bacterium. Predicted to be located in extracellular space. Is expressed in embryonic/larval midgut. Orthologous to human LYZ (lysozyme). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See LysX in Genome Data Viewer
    Location:
    61F3-61F3; 3-0 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (1194739..1195302, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (1194739..1195302, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene bric a brac 2 Neighboring gene uncharacterized protein Neighboring gene Tryptophan hydroxylase neuronal Neighboring gene APPL-interacting protein 1 Neighboring gene meep Neighboring gene multiple wing hairs

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The lysozyme locus in Drosophila melanogaster: an expanded gene family adapted for expression in the digestive tract. Daffre S, et al. Mol Gen Genet, 1994 Jan. PMID 8159165
    2. Insect lysozymes. Hultmark D. EXS, 1996. PMID 8765296
    3. Molecular adaptation of Drosophila melanogaster lysozymes to a digestive function. Regel R, et al. Insect Biochem Mol Biol, 1998 May-Jun. PMID 9692234
    4. Expression patterns of cardiac aging in Drosophila. Cannon L, et al. Aging Cell, 2017 Feb. PMID 28090760, Free PMC Article
    5. Characterization of the c-type lysozyme gene family in Anopheles gambiae. Li B, et al. Gene, 2005 Nov 7. PMID 16137842

    See all (54) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables lysozyme activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables lysozyme activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables lysozyme activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in defense response to Gram-negative bacterium ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in extracellular space ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    lysozyme X
    Names
    CG9120-PA
    LysX-PA
    NP_523881.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      1194739..1195302 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_079157.2 → NP_523881.1  lysozyme X [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_523881.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A4V9W9, A4V9X0, A4V9X1, A4V9X2, P37161, Q9W0K1
      UniProtKB/TrEMBL
      A0A1B2AJT6
      Related
      FBpp0072533
      Conserved Domains (1) summary
      cl00222
      Location:20 → 140
      lysozyme_like; lysozyme_like domain. This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases. ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P37161.2 P37161

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