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    CG9876 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37668, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG9876provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0034821
    Locus tag
    Dmel_CG9876
    See related
    AllianceGenome:FB:FBgn0034821
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG9876
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Is expressed in embryonic/larval oenocyte; embryonic/larval posterior spiracle; oenocyte primordium; prothoracic gland; and sensory nervous system primordium. Human ortholog(s) of this gene implicated in agnathia-otocephaly complex. Orthologous to several human genes including PRRX1 (paired related homeobox 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG9876 in Genome Data Viewer
    Location:
    59C3-59C3; 2-102 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (23090100..23094266, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (18977623..18981789, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Ribosomal protein L37-2 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Lpt, trr, and Hcf regulate histone mono- and dimethylation that are essential for Drosophila heart development. Huang W, et al. Dev Biol, 2022 Oct. PMID 35853502, Free PMC Article
    2. Homeobox gene clusters and the human paralogy map. Popovici C, et al. FEBS Lett, 2001 Mar 2. PMID 11240134
    3. The EH1 motif in metazoan transcription factors. Copley RR. BMC Genomics, 2005 Nov 27. PMID 16309560, Free PMC Article
    4. A large-scale resource for tissue-specific CRISPR mutagenesis in Drosophila. Port F, et al. Elife, 2020 Feb 13. PMID 32053108, Free PMC Article
    5. Homeodomain proteins: an update. Bürglin TR, et al. Chromosoma, 2016 Jun. PMID 26464018, Free PMC Article

    See all (34) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG9876-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      23090100..23094266 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_137912.2 → NP_611756.1  uncharacterized protein Dmel_CG9876 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611756.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7YU61, Q9W1U7
      Related
      FBpp0071889
      Conserved Domains (1) summary
      pfam00046
      Location:121 → 173
      Homeobox; Homeobox domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7YU61 Q7YU61
    Q9W1U7 Q9W1U7

    Gene LinkOut

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